Shape of female reproductive tract weeds out weak sperm
Slower sperm are beaten by stronger and faster sperm when competing to fertilise an egg due to restrictive bottlenecks in the female reproductive tract...
BioNews
In vivo
Latin for 'within the living', referring to processes taking place within a living organism.
51 articles
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
First in-body genome editing trial delivers mixed results
The first in vivo genome editing therapy has been successful in editing patients' DNA, but has not shown a clinical benefit...
Book Review: Regulating Assisted Reproductive Technologies - New Horizons
In 'Regulating Assisted Reproductive Technologies: New Horizons', Dr Amel Alghrani explores the future regulation of new reproductive technologies, specifically ectogenesis — gestating a fetus outside of a human body in an artificial womb, and uterus tr
'Artificial ovary' for humans passes key milestone
Scientists have successfully supported human follicles — the precursors of egg cells — on a bioengineered ovarian 'scaffold' for the first time. The work is an important proof-of-concept, which may pave the way for developing artificial ovaries for
Image by K Hardy via the Wellcome Collection. Depicts a human embryo at the blastocyst stage (about six days after fertilisation) 'hatching' out of the zona pellucida.
In depth: Our first look at the human development 'organiser cells'
Almost a century ago, Professor Hans Spemann, a German biologist from the University of Freiburg, and his PhD student Hilde Mangold defined a group of cells in newt embryos that triggered development of the central nervous system...
Silencing a prostate cancer gene kills tumour cells
A recent study identifies a new molecule as a potential target for prostate cancer therapy...
Genome editing could slow the growth of pancreatic cancer
Researchers have slowed the growth of pancreatic cancer by harnessing genome editing to remove key molecules implicated in its spread...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Genetic 'sensor' spots and kill cells with key cancer gene
A team of scientists in Germany has developed a 'sensor' that detects mutations in the key tumour suppressor gene p53 and then kills potentially cancerous cells...
RNA editing with CRISPR could treat genetic diseases
Scientists have repurposed CRISPR to target the repetitive RNA sequences responsible for several genetic diseases...
Gene therapy skin grafts for obesity and diabetes
A proof-of-concept study in mice has demonstrated how skin grafts could deliver gene therapy for obesity and diabetes...