A knockout is a laboratory animal in which researchers have inactivated, or 'knocked out,' an existing gene by replacing it or disrupting it with an artificial piece of DNA.
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Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Genes that could be involved in heart development have been identified using a method that looks for candidate genes not solely expressed in heart tissue.
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