The birth of genetics: celebrating 200 years of Mendel
Professor Frances Flinter, emeritus professor of clinical genetics at Guy's and St Thomas' NHS Foundation Trust discusses Gregor Mendel's life and works, 200 years after his birth...
BioNews
Polygenic
Relating to a condition or trait influenced by the combined effects of multiple different genes.
81 articles
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Event Review: Fertility 2022 – Challenges with embryo selection using polygenic scores
The use of polygenic risk scores for embryo selection has come up repeatedly over the past year so I was excited to attend a talk on the subject at the Fertility 2022 conference...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Preimplantation genetic testing proposed to predict risk of common diseases
A new study claims to be able to map the genomes of embryos created by IVF, and suggests the technique could be used for preimplantation genetic testing...
Lawfully running a red light: a response from the HFEA
In last week's BioNews, Julian Hitchcock argued that a recent statement from the Human Fertilisation and Embryology Authority on embryo selection needed clarification. I am happy to do that today...
No evidence for using polygenic risk scores in embryo selection
The use of polygenic risk scores to select embryos is being advertised and sold by some private fertility clinics...
NHS pilot to test polygenic scores as a screening tool
The NHS has launched a world-first pilot study of predictive genomic testing for the prevention of cardiovascular disease...
Alzheimer's may be detectable before symptoms appear
Healthy people with an inherited risk of Alzheimer's disease show structural brain differences before the onset of symptoms...
Genetic testing advances revealed at European Human Genetics Conference
Genetic testing could prove useful for determining a diagnosis and prognosis for people with epilepsy, attendees at the European Society of Human Genetics conference heard...
Genetic research suggests men can develop polycystic ovary syndrome symptoms
Men carrying genetic risk factors for polycystic ovary syndrome (PCOS) are more likely to develop diabetes, obesity and male-pattern baldness...
NHS launches polygenic scores pilot to calculate heart disease risk
The NHS is to trial a new approach in personalised medicine that aims to help calculate patients' individual risk for heart disease...