The physical shape of DNA in a cell influences the rate of unintended, off-target effects of CRISPR/Cas9 genome editing...
In this short film – shown at the Science Museum in London, as part of the official 60th anniversary celebrations of Star Trek – Professor Robin Lovell-Badge discusses the real-life events that inspired the fictional Shenzhen Convention...
Metabolic disorders can seem forbiddingly complex, but a simplified approach to explaining their biological basis can lead to improved understanding, earlier diagnosis and better management, argues Dr Srividya Sreekantam...
A lipid nanoparticle-based gene therapy for cystic fibrosis restores biological function in a preclinical model...
This film documents a PET event discussing how to improve diagnosis, treatment and support for people affected by rare and inherited metabolic diseases...
A topical CRISPR-based genome-editing therapy has been developed to address disease-causing mutations responsible for inherited human skin disorders...
Professor Jim Al-Khalili interviews Professor George Church in this episode of The Life Scientific. From bringing back mammoths to the Human Genome Project... but does he ask probing enough questions? Davy Tennison finds out for BioNews...
A novel gene insertion therapy to treat a rare liver disorder in newborns has received regulatory designations in the USA and the UK...
Ancient viral DNA sequences in the mouse genome may offer insight into a severe muscle-wasting disease in humans…
A patient with B-cell acute lymphoblastic leukaemia has become the first adult to receive a pioneering cell therapy on the NHS...
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