Transcription factor position determines gene activity
'Spatial grammar' within our DNA code has been uncovered, which could change our understanding of how genes are activated...
Dr Olivia Goff is a Volunteer Writer at BioNews, having originally joined the publication under the auspices of its writing scheme. She obtained a PhD in Neuroscience from University College London's Queen Square Institute of Neurology, where she worked in the laboratory of Professor Dimitri Kullmann, within the Department of Clinical and Experimental Epilepsy. Her research specifically aimed to develop novel gene therapies to treat refractory, focal epilepsy. She previously obtained a BSc in Biochemistry from the University of Bristol. Alongside her research, Olivia is a green representative for her department exploring ways in which the labs can employ more sustainable ways of working.
'Spatial grammar' within our DNA code has been uncovered, which could change our understanding of how genes are activated...
A CRISPR genome-editing therapy has been shown for the first time to provide long-term genome correction in lung cells for treatment of cystic fibrosis in mice...
Delivering short electrical pulses to cells has been shown to increase the susceptibility of cells to take in gene therapy, potentially reducing the dosage required...
A protein involved in DNA damage repair, PARP1, has been likened to superglue due to its crucial role in holding together the broken DNA ends...
A rhesus monkey has been successfully cloned and has become the first of its kind to reach adulthood, Chinese scientists have revealed...
More than 200 new genes associated with depression have been identified in the first large-scale genome-wide association study to include participants from diverse ancestry groups...
The past, present and future of gene therapies is discussed in this Pulse podcast...
Whole genome sequencing data from 500,000 British volunteers has been released globally by UK Biobank, for scientific research...
Over 100,000 DNA samples require re-examination following the discovery of fundamental flaws in an Australian state-run forensic laboratory...
CRISPR base editing therapy reduced cholesterol levels in the blood of a small cohort of patients, clinical trial interim data has shown...
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