ICSI and ovarian stimulation linked to different patterns in children's DNA
Parental age and various procedures used during assisted reproductive technology have been linked to different patterns of mutational changes in the DNA of offspring...
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Image by Matthew Daniels, via the Wellcome Collection. Depicts a human (HeLa) cell in metaphase (the chromatin is stained red and the microtubules forming the spindle are stained green).
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Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Human jumping gene found in poxvirus genome
A primate-specific gene known as BC200 has been found to have 'jumped' into a human virus from the pox family...
British patients left in limbo after Portuguese IVF clinic closes
UK patients have had their fertility treatment disrupted after a Portuguese fertility clinic was declared insolvent...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Salivary gland organoids developed from human pluripotent stem cells
Human salivary gland organoids derived from pluripotent stem cells have been transplanted into mice....
Better birth outcomes after fertility treatment for single mothers by choice
Birth outcomes for single mothers who conceive using fertility treatments are at least comparable to those of mothers who conceive naturally or partnered mothers who had fertility treatment, and in some instances more favourable...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Human brain develops from two distinct groups of cells
The origins of the human brain can be traced back to two distinct groups of cells in the developing embryo...
Image by Bill Sanderson via the Wellcome Collection, © Wellcome Trust Ltd 1990. Depicts Laocoön and his family (from Greek and Roman mythology) entwined in coils of DNA.
UK Government to offer bereavement leave after failed IVF transfers
The UK Government has announced plans to give employees in Great Britain a legal right to bereavement leave following pregnancy loss, including miscarriage and unsuccessful IVF embryo transfers...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Gene therapy improves low-light vision in patients with rare retinal condition
A Phase 2/3 trial assessing a gene therapy for X-linked retinitis pigmentosa (XLRP) shows significant improvements in low-light vision...
Following birth of baby, parents allege that a Florida IVF clinic used the wrong sperm
A Florida couple is suing a fertility clinic after genetic analyses revealed that their daughter is not biologically related to her father...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Mapping DNA in 3D yields insights into Alzheimer's disease
Single-cell approaches show that alterations in the 3D architecture of the genome are tied to changes in gene activity in Alzheimer's disease...