Genome editing reactivates zeta-globin gene in alpha-thalassaemia
Switching back on a gene that is normally silenced early in development has improved features of severe alpha-thalassaemia in mice and restored globin production in cells from patients...








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All CommentA tribute to Dr Marta Shahbazi (1985-2026)
by Sarah Norcross and 1 others
The director and deputy director of PET pay tribute to Dr Marta Shahbazi – a prominent and inspiring figure in human embryo research, who was killed in last week's rail collision in Spain...
When our embryos were labelled 'abnormal', we lost the right to choose
by Dr Shizuko Takahashi
Fertility physician, clinical geneticist, and bioethicist Dr Shizuko Takahashi questions why PGT-A is being used to limit – rather than inform – patient choices...
To err is human: How human embryos rarely get it right
by Dr Aleksandra Byrska
Dr Aleksandra Byrska explores why human embryos are prone to chromosomal errors and how these might affect IVF success...
PET Podcast: The Genetics of Infertility – Causes, Choices and Treatments
by Sarah Norcross
Bringing you PET events as a podcast. In the 54th episode of its podcast, PET explores the genetics and genomics of infertility, with Professor Willem Verpoest, Professor Stéphane Viville, Professor Joris Veltman and Professor Micheline Misrahi...
A quiet morning inside the black box: A chance at life
by Katharina Stock
Katharina Stock, first prize winner in this year's Marcus Pembrey BioNews Writing Competition, explores how AI is being used to select embryos during IVF. Who – if anyone – is accountable for the resulting decision?...