PET PET
  • My Account
  • Subscribe
Become a Friend Donate
  • About Us
    • People
    • Press Office
    • Our History
  • Get Involved
    • Become a Friend of PET
    • Volunteer
    • Campaigns
    • Writing Scheme
    • Partnership and Sponsorship
    • Advertise with Us
  • Donate
    • Become a Friend of PET
  • BioNews
    • News
    • Comment
    • Reviews
    • Elsewhere
    • Topics
    • Glossary
    • Newsletters
  • Events
    • Upcoming Events
    • Previous Events
  • Engagement
    • Policy and Projects
      • Resources
    • Education
  • Jobs & Opportunities
  • Contact Us
  • About Us
    • People
    • Press Office
    • Our History
  • Get Involved
    • Become a Friend of PET
    • Volunteer
    • Campaigns
    • Writing Scheme
    • Partnership and Sponsorship
    • Advertise with Us
  • Donate
    • Become a Friend of PET
  • BioNews
    • News
    • Comment
    • Reviews
    • Elsewhere
    • Topics
    • Glossary
    • Newsletters
  • Events
    • Upcoming Events
    • Previous Events
  • Engagement
    • Policy and Projects
      • Resources
    • Education
  • Jobs & Opportunities
  • Contact Us
  • My Account
  • Subscribe
  • Privacy Statement
  • Advertising Policy
  • Thanks and Acknowledgements
PETBioNewsNewsFirst DNA test for 'personalised medicine' launched

BioNews

First DNA test for 'personalised medicine' launched

Published 9 June 2009 posted in News and appears in BioNews 276

Author

BioNews

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.

A genetic test that helps predict how people will react to certain medicines has been approved for sale in the European Union, Swiss firm Roche Diagnostics has announced. The test, called the AmpliChip CYP450, detects variations in two genes that make key liver enzymes. Variations in the activity of these...

A genetic test that helps predict how people will react to certain medicines has been approved for sale in the European Union, Swiss firm Roche Diagnostics has announced. The test, called the AmpliChip CYP450, detects variations in two genes that make key liver enzymes. Variations in the activity of these enzymes are responsible for different reactions to many commonly used drugs. Some people, classed as 'poor metabolisers', may not break a drug down quickly enough, and so could suffer side effects, whereas in 'fast metabolisers' the same drug may be broken down before it has chance to work.


The test looks at the genes CYP2C19 and CYP2D6, and is sold as a DNA microarray - a thumbnail-sized glass 'chip' with DNA fragments arranged on it. The test detects the likely response to a wide range of drugs, including many anti-depressants, anti-psychotics, painkillers, beta-blockers, anti-convulsants and anti-malarial drugs. Roche says that with the launch of the new test 'we are on our way to helping physicians move toward a more personalised approach to therapy'.


Pharmacogenetics - medicines tailored to a person's genetic make-up - has often been touted as the future of healthcare. Earlier this year, UK Health Minister Lord Warner announced that research into pharmacogenetics is to receive £4 million of funding. The new test is the first real example of how this technology might help doctors to prescribe the most suitable medicines for their patients. 'As far as I'm aware, this is the first commercial diagnostic test for personalised medicine', Doris-Ann Williams, of the British In Vitro Diagnostics Association, told New Scientist magazine. However, she added that at around €450 per test, the cost of the AmpliChip CYPP450 will mean it is only an option for wealthier patients.

Related Articles

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
9 June 2009 • 2 minutes read

Personalised medicine 15-20 years away, say UK scientists

by BioNews

The UK's Royal Society has published a report on the potential of pharmacogenetics - drug treatments tailored to a person's genetic make-up - following a year-long investigation into the subject. It concludes that although 'personalised medicines' have a promising future, it will be at least another 15-20 years before their use...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
9 June 2009 • 2 minutes read

'Desk-top' machine for personalised prescriptions

by BioNews

Japanese companies have built a desk-top machine that allows doctors to check their patients' DNA before writing a prescription, the journal Nature reports. The device, which they say will be on sale for five million yen (£25,000) in a year's time, uses a single drop of blood and delivers results...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
9 June 2009 • 1 minute read

Pharmacogenetic test approved in US

by BioNews

A 'gene chip' test that helps predict how people will react to certain medicines has now been approved for sale in the US by the Food and Drug administration (FDA). The AmpliChip Cytochrome P450, launched in 2003 by Swiss firm Roche Diagnostics, is one of the first commercial applications of...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
9 June 2009 • 1 minute read

Inquiry into 'personalised medicine' launched

by BioNews

The UK's Royal Society is launching a year-long investigation into the potential of pharmacogenetics: drug treatments tailored to a person's genetic make-up. The study, headed by geneticist Sir David Weatherall, will look at when and if 'personalised medicine' will become a reality. It will also assess whether healthcare providers in...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
9 June 2009 • 1 minute read

Cash boost for personalised medicines

by BioNews

Research into pharmacogenetics - the use of genetic tests to match medicines to a person's genetic make-up - is to receive £4 million of funding, Health Minister Lord Warner announced last week. The cash will go to six different research projects, which include studies on medicines used to prevent blood clots, epilepsy...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
9 June 2009 • 1 minute read

Hype and hope for personalised medicines

by BioNews

A new report concludes that that the marketing of pharmacogenetic tests - matching medicines to a person's genetic make-up - may be moving faster than the underlying science. The findings, entitled 'My very own medicine: What must I know?' were published recently by the Department of Public Health and Primary Care at...

Leave a Reply Cancel reply

You must be logged in to post a comment.

« Singapore bans reproductive cloning

Data-Label The UK's Leading Supplier Of Medical Labels & Asset Labels

RetiringDentist.co.uk The UK's Leading M&A Company.
easyfundraising
amazon

This month in BioNews

  • Popular
  • Recent
13 June 2022 • 2 minutes read

Drop in diversity of blood stem cells leads to old-age health issues

27 June 2022 • 2 minutes read

UK report reveals public attitudes to fertility, genomics and embryo research

27 June 2022 • 2 minutes read

Shortage of sperm donors despite men willing to donate

27 June 2022 • 2 minutes read

North East London CCG proposes offering three funded IVF cycles

27 June 2022 • 2 minutes read

Fibrosis drugs reverse ovarian ageing in mice

27 June 2022 • 2 minutes read

Gene implicated in motor neurone diseases discovered

Subscribe to BioNews and other PET updates for free.

Subscribe
  • Twitter
  • Facebook
  • Instagram
  • LinkedIn
  • YouTube
  • RSS
Wellcome
Website redevelopment supported by Wellcome.

Website by Impact Media Impact Media

  • Privacy Statement
  • Advertising Policy
  • Thanks and Acknowledgements

© 1992 - 2022 Progress Educational Trust. All rights reserved.

Limited company registered in England and Wales no 07405980 • Registered charity no 1139856

Subscribe to BioNews and other PET updates for free.

Subscribe
PET PET

PET is an independent charity that improves choices for people affected by infertility and genetic conditions.

  • Twitter
  • Facebook
  • Instagram
  • LinkedIn
  • YouTube
  • RSS
Wellcome
Website redevelopment supported by Wellcome.

Navigation

  • About Us
  • Get Involved
  • Donate
  • BioNews
  • Events
  • Engagement
  • Jobs & Opportunities
  • Contact Us

BioNews

  • News
  • Comment
  • Reviews
  • Elsewhere
  • Topics
  • Glossary
  • Newsletters

Other

  • My Account
  • Subscribe

Website by Impact Media Impact Media

  • Privacy Statement
  • Advertising Policy
  • Thanks and Acknowledgements

© 1992 - 2022 Progress Educational Trust. All rights reserved.

Limited company registered in England and Wales no 07405980 • Registered charity no 1139856