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PETBioNewsGlossarySNP (single nucleotide polymorphism)

BioNews

SNP (single nucleotide polymorphism)

An SNP (single nucleotide polymorphism) is a single chemical unit (base pair) variation in a stretch of DNA, present in more than 1% of the population. A common SNP is estimated to occur 1 in every 1000 base pairs between any two people.

162 articles
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
19 November 2021 • 2 minutes read

200,000 whole genomes sequenced by UK Biobank available to researchers

by Dr Molly Godfrey

The first 200,000 whole genomes to be sequenced as part of the UK Biobank project have been made widely available to researchers...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
8 October 2021 • 2 minutes read

Genetic variant increases Alzheimer's and severe COVID-19 risk

by Semyon Bodian

A gene variant has been identified that is linked to the development of both Alzheimer's and severe COVID-19, new research has found...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
25 February 2021 • 2 minutes read

Newlywed's satisfaction may be linked to a genetic variant

by Martha Roberts

Psychologists have found a genetic variant associated with relationship satisfaction in the first years of marriage...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
Reviews
25 September 2020 • 4 minutes read

Event Review: The Genetics of Mental Health — Episode one

by Martha Roberts

We get a great deal of mileage out of the terms 'nature' and 'nurture', even though thinking about evolution, human beings, and life using these supposedly distinct and mutually exclusive labels is surely a gross simplification...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
6 December 2019 • 2 minutes read

Junk DNA may affect cancer risk

Scientists have found that genetic variation in regions of DNA that do not code for proteins, previously characterised as 'junk DNA', may affect a person's risk to develop a form of inherited cancer...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
Reviews
28 October 2019 • 4 minutes read

Podcast Review: The Dangers of DIY Genetic Testing (Science Weekly, The Guardian)

by Dr Laura Riggall

By 2022 the world's consumer genetic testing market is expected to quadruple to £200 million, according to The Guardian. But while the popularity of DIY genetic testing has undergone huge expansion in recent years, doctors and scientists have called for a crackdown on tests offered by consumer genetics companies such as 23andMe and AncestryDNA...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
25 October 2019 • 3 minutes read

Study suggests 'gene drain' from Britain's industrial areas

by Julianna Photopoulos

A new study suggests a 'gene drain' linked to social migration in Great Britain, where people with a genetic predisposition for higher educational attainment are more likely to leave former industrial regions and live in wealthier areas...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
29 July 2019 • 2 minutes read

NHS 'genomic volunteers' won't be expected to pay for genome sequencing

by Jen Willows

Two new government publications reveal that plans to charge healthy volunteers for NHS genome sequencing have been scrapped...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
22 July 2019 • 3 minutes read

Experts speak out on direct-to-consumer genetic testing

by Shaoni Bhattacharya

Geneticists in the UK have been speaking out against direct-to-consumer DNA testing after concerns over false positive results...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
Comment
1 July 2019 • 4 minutes read

What can healthy individuals learn from getting their genomes sequenced?

by Dr Jess Buxton

The past few years have seen a huge increase in the identification of rare and common genetic variants associated with disease, advances made possible through ever cheaper and faster genome sequencing technologies...

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