Extra chromosomal DNA in tumours fuels cancer growth
Circular DNA existing outside chromosomes can drive cancer growth and is a potential drug target, according to three papers published this week in Nature...
Research Associate at the Early Cancer Institute
Dr Daniel Jacobson is a Volunteer Writer at BioNews, having originally joined the publication under the auspices of its writing scheme. He is now a Research Associate at the Early Cancer Institute at the University of Cambridge, studying the evolution of gastric and oesophageal cancer. Previously, he completed his PhD in computational cancer genetics at University College London (UCL), as part of the UCL-Birkbeck MRC Doctoral Training Partnership, where he was using machine learning and cancer genomics data to study drug sensitivity and resistance in breast cancer. He previously obtained an MSci in Natural Sciences, also at UCL, and is a keen science writer and communicator, as well as a culture writer. He tweets as @DanH_Jacobson
Circular DNA existing outside chromosomes can drive cancer growth and is a potential drug target, according to three papers published this week in Nature...
Genome editing using small protein structures has the potential to be more efficient, with increased specificity, than current methods – such as CRISPR/Cas genome editing...
A machine learning tool has inferred risk factors associated with over one thousand diseases, offering the possibility for improving early disease detection and drug discovery...
Adverse effects from immunotherapy treatment in melanoma patients are associated with a distinct pattern of gene expression, offering the possibility for improved therapeutic strategies...
New ways in which genes can be 'misexpressed' have been uncovered in healthy patients, offering opportunities to study and treat complex diseases...
Routine whole genome sequencing can improve treatment options for children with cancer, according to a recent NHS trial...
A new biological pathway linked with inflammatory bowel disease has been discovered, offering new opportunities for treatments...
The number of copies of ribosomal DNA a person has, has been linked to multiple disease-associated traits...
A new 'personalised' treatment for melanoma, based on the same technology behind the COVID-19 vaccines, is now in Phase 3 trials in the UK...
Dr Dan Jacobson finds this 'high-minded, critically-polarising, French, visually-stunning-yet-powerfully-moody exploration of human existence' bold, fascinating and more than occasionally unintelligible...
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