A pair of complementary bases (chemical units that form DNA) in a double-stranded nucleic acid molecule.
In DNA, the base adenine (A) always pairs with thymine (T) and the base cytosine (C) always pairs with guanine (G).
A genome editing technique has corrected a disease-causing mutation in blood stem cells taken from a patient with a rare and severe immune disorder...
Base editing can efficiently alter the DNA of human embryos, but it can also result in unintended genomic changes....
A topical CRISPR-based genome-editing therapy has been developed to address disease-causing mutations responsible for inherited human skin disorders...
A novel artificial intelligence tool has been developed to predict the molecular and regulatory effects of genetic variants relevant to health and disease...
A detailed integrated map of the human genome's 3D structure over time shows how DNA structure is linked to gene activity...
The 3D structure of the human genome has been mapped at the level of individual bases, defining complex structures which control how DNA functions within the cell...
James Watson, the co-discoverer of the DNA double helix structure, has died at the age of 97...
Synergistic evidence from two studies published in Nature this week have updated our understanding of the human genome...
Dr Franklin Stahl, a prominent molecular biologist whose work helped solidify the DNA double helix model, has died aged 95...
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