Scientists have discovered a gene mutation that can predispose carriers to one of the most common forms of epilepsy, bringing hope that new treatments for the disorder will be able to be developed. Canadian researchers discovered that the mutated gene, GABRA1, was present in eight members of a French-Canadian family who had similar experiences of epilepsy. Six members of the same family, who do not have epilepsy, also do not have the mutation.
It has also been reported that US scientists have discovered that a missing or defective combination of genes involved in lung cancer, when replaced using gene therapy in mice, slowed the development of the cancer, or cured the mice altogether. The researchers hope to begin experiments on humans, using the same technique, within a year.
Meanwhile, researchers at Heidelberg University in Germany have found that mice which lack a particular gene are more likely to consume alcohol following a stressful experience. Reporting their findings in the journal Science, they suggest that humans lacking the same gene, CRH1, may have similar reactions to stress. It is hoped that the discovery may lead to better diagnosis and treatment of alcoholics, particularly those who are recovering but may be in danger of relapse.
Sources and References
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Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors
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Epilepsy gene identified
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Genes may drive stressed-out drinkers
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Three genes may slow lung cancer
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