Tracing the development of CRISPR/Cas genome editing

The ability to easily and accurately edit DNA in cells and organisms has transformed basic biology research, medicine and biotechnology.

The CRISPR/Cas9 system as a genome editing method was discovered in 2012 by Professor Jennifer Doudna, of UC Berkely and Professor Emmanuel Charpentier, of the Max Planck Institute, Berlin, Germany.

Now, Professors' Doudna and Charpentier have written a review in Science explaining how the CRISPR/Cas system was developed into an easy-to-use approach for editing DNA.