Making deliberate alterations to the DNA sequence at targeted locations in the genome. This can include deleting, inserting or replacing sections of DNA. Several approaches are used to achieve these changes, include zinc finger nucleases (ZFNs), TALENs, CRISPR/Cas and base editing.
In this podcast from the Economist, science editor Alok Jha speaks to Professor Jennifer Doudna, joint Nobel prize winner alongside Professor Emmanuelle Charpentier in chemistry, about her work on the genome editing approach CRISPR.
The use of CRISPR genome editing in immune cells increases genomic instability, which may be a risk factor for cancer, according to new research...
A novel gene therapy which uses base-editing to lower cholesterol has been given to the first patient in a clinical trial...
Ethicists, Professor Wybo Dondorp and Professor Guido de Wert, summarise the 2021 evaluation of the Dutch Embroys Act with regard to the legal definition of an embryo, and how this relates to the recommendation to lift the ban on creating embryos for research...
The safety and efficiency of CRISPR-based genome editing may be improved by using an enzyme that cuts just one strand of DNA instead of both...
Discrepancies between public opinion and real-world access to fertility services in the UK have been highlighted by a fertility and genomics survey commissioned by the Progress Education Trust...
A recent episode of Genetics Unzipped 'Have a heart: the science of xenotransplantation' talked about the process of transplanting organs from animals into human bodies...
BioNews, published by the Progress Educational Trust (PET), provides news and comment on genetics, assisted conception, embryo/stem cell research and related areas.
