A genome-editing platform that uses an enzyme (Cas9) to make a double-stranded break at a specific location in the genome, directed by a guide RNA.
Using base editing, a highly precise method of genome editing, scientists have investigated the role of the NANOG gene in human embryos for the first time with this approach...
Former consultant embryologist Jane Blower was recognised in this year's King's Birthday Honours List alongside Professors Andrew Mumford, Bruce Whitelaw and Gareth Evans...
A transplant of genome-edited stem cells designed to protect healthy donor cells from cancer therapy has shown promise in patients with aggressive blood cancers...
A single-dose CRISPR-based genome-editing therapy for hereditary angioedema has shown positive Phase 3 clinical trial results and entered a step-by-step approval process with US regulators...
A new CRISPR-based approach has been designed to selectively eliminate human cells with disease-causing genes in vitro...
The physical shape of DNA in a cell influences the rate of unintended, off-target effects of CRISPR/Cas9 genome editing...
A lipid nanoparticle-based gene therapy for cystic fibrosis restores biological function in a preclinical model...
CRISPR/Cas9 genome editing has been used in mice to investigate two key genes' roles in male fertility and sperm production...
A new genome editing approach has been shown to safely and efficiently remove the source of transthyretin amyloidosis in mice, demonstrating greater therapeutic opportunities for genome editing...
Data on the effectiveness and safety of Casgevy gene therapy in children aged five to 11 years has been reported...
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