A genome-editing platform that uses an enzyme (Cas9) to make a double-stranded break at a specific location in the genome, directed by a guide RNA.
A genome editing technique has corrected a disease-causing mutation in blood stem cells taken from a patient with a rare and severe immune disorder...
The discovery of a new gene-targeting system used by viruses to fend off competitors gives a glimpse into the possible evolutionary origin of CRISPR, and may offer new opportunities for genome editing technologies...
Base editing can efficiently alter the DNA of human embryos, but it can also result in unintended genomic changes....
A genetically modified pig kidney has functioned inside a living patient for a record nine months, successfully serving as a temporary bridge to a subsequent human donor transplant for the first time...
Behind every scientific breakthrough is a story. Dr Oliver Bower, the lead author of a recent Nature study, describes how listening to people affected by genetic disease reshaped his research and his perspective on the future of genome editing...
Using base editing, a highly precise method of genome editing, scientists have investigated the role of the NANOG gene in human embryos for the first time with this approach...
Former consultant embryologist Jane Blower was recognised in this year's King's Birthday Honours List alongside Professors Andrew Mumford, Bruce Whitelaw and Gareth Evans...
A transplant of genome-edited stem cells designed to protect healthy donor cells from cancer therapy has shown promise in patients with aggressive blood cancers...
A single-dose CRISPR-based genome-editing therapy for hereditary angioedema has shown positive Phase 3 clinical trial results and entered a step-by-step approval process with US regulators...
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