Could delivering messenger RNAs into blood stem cells treat sickle cell without the need for a risky stem cell transplant? Or could they even be used to deliver a targeted base editing solution? William A Haseltine, writing in Forbes, discusses the potential for such an approach.
An mRNA treatment for sickle cell?
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
