Could delivering messenger RNAs into blood stem cells treat sickle cell without the need for a risky stem cell transplant? Or could they even be used to deliver a targeted base-editing solution? William A. Haseltine, writing in Forbes, discusses the potential for such an approach.
An mRNA treatment for sickle cell?
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
