DNA duplications and deletions don't bridge 'heritability gap'
A study investigating the effects of common large DNA deletions and duplications has found no new links to complex disease...
BioNews
CNV (copy number variation)
CNV (copy number variation) refers to segments of DNA larger than 1kb (1000 base-pairs) that vary in copy number between individuals. CNVs that encompass one or more genes can influence susceptibility to disease and other traits.
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Rare gene mutation blamed for some childhood obesity
A rare gene mutation may explain the weight of some severely overweight young children, a study has found. The new findings have already affected when social workers judge children to be deliberately overfed or neglected...
Gene clue to neuroblastoma
Neuroblastoma, a form of paediatric cancer which affects the nervous system, may be caused by copy number variations (CNVs) in genes which control nervous system development. The research, published last week in Nature, suggests a different genetic mechanism for cancers than was previously proposed. Dr John Maris who led the study at the University of Pennsylvania, Philadelphia, US, said 'We can infer that it's not just going to be true for neuroblastoma. My expectation is that there will be ...