Children aged five and older with severe sickle cell disease or transfusion-dependent beta-thalassaemia can now receive cell-based gene therapy Casgevy after the UK extended its authorisation to include eligible younger children...
A large international study of 2.8 million people identified new Alzheimer's disease risk regions – furthering our understanding of the genetic and biological mechanisms underlying the disease...
A gene located on the X chromosome could affect how autism manifests, potentially offering an explanation for the sex-based differences in autism prevalence...
Age-related changes in gene expression have revealed molecular clues about male fertility in new research...
Dr Desislava Staneva reviews The Second Creation, exploring the science behind Dolly the sheep, the history of cloning and how genome editing has changed the field…
Switching back on a gene that is normally silenced early in development has improved features of severe alpha-thalassaemia in mice and restored globin production in cells from patients...
Mouse study sheds light on the biological pathway that could underpin brain impairments in Angelman syndrome, potentially revealing a new therapeutic target...
The US Food and Drug Administration has outlined a framework that could allow multiple related, patient-specific genome editing therapies to be covered by a single approval, for patients with different genetic variants of the same gene...
Dr Kate Sheridan Clay, second prize winner in this year's Marcus Pembrey BioNews Writing Competition, explores how PGT-P promises parents greater control over their future children's health and traits. What happens when the embryo they choose fails to fulfil their expectations?...
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