CRISPR/nickase genome editing more efficient and efficient than CRISPR/Cas9
The safety and efficiency of CRISPR-based genome editing may be improved by using an enzyme that cuts just one strand of DNA instead of both...
Proteins produced by a living organism which act to bring about, or increase the rate of, a specific biochemical reaction.
The safety and efficiency of CRISPR-based genome editing may be improved by using an enzyme that cuts just one strand of DNA instead of both...
Dopamine-producing cells created from induced pluripotent stem cells and transplanted into rats with Parkinson's disease, successfully alleviated symptoms, a new study has shown...
The first team to use CRISPR to edit a disease-causing gene in humans has found the effects are persistent up to a year later...
Gene therapy given to children affected by the fatal neurological disorder Tay-Sachs disease is safe and stabilises disease progression, reports an exploratory proof-of-concept study...
The Centre for Bioethics and Harvard Medical School, Massachusetts, presented a fascinating talk on the opportunities for great medical advancements, and grave harm, presented to researchers by CRISPR/Cas9 and other apporaches to genome editing...
by Abbie Harper
DNA with knot-like structures and third rungs between the two strands may drive cancer development, with an important regulatory enzyme involved in the formation of these structures...
Gene expression during early development of primordial germ cells is sex-specific...
Gene therapy delivered to a novel mouse model of Parkinson's disease improved the effects of existing Parkinson's drug levodopa...
Splitting and reconstituting the enzymes used in the base editing method of genome editing may make more controlled changes possible...
Inflammation of certain neurons in the hypothalamus region of the brain is responsible for reduced sperm counts in male mice exposed to high-levels of air pollution, scientists have shown...
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