Donor Conception and Genetic Disease: Lessons to Be Learned from Donor 7069
Seven experts discussed the sensitive case of donor 7069 and explored what could be done to avoid it happening again, as well as how to improve outcomes if it did...
BioNews
Genetic variant
A relatively common (present in more than 1% of the population) alternative version of a DNA sequence. Some variants are associated with particular traits and disorders, but many have no observable effect on appearance or health.
695 articles
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Expanded carrier screening: Reflections on new guidance
The British Fertility Society has issued new guidance which provides direction on genetic testing in gamete donation in the UK...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Infant receives first-in-human gene therapy for severe genetic epilepsy
A new experimental gene therapy has shown early success in treating a rare genetic epilepsy syndrome...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Podcast Review: Centre for Personalised Medicine – Equity
What if personalised medicine – designed to be more precise – actually ends up being less fair, asks Dr Tsveti Stoilova...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
NHS pharmacogenomic test improved for patients of African ancestry
A routine genetic test used by the NHS to guide prescription of a common chemotherapeutic drug now includes a genetic variant more prevalent in people of African descent...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Recessive gene variant causes neurodevelopmental disorder
A newly described neurodevelopmental disorder has been linked to changes in a small noncoding gene...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Patients' genetics shape response to GLP1 drugs
Two genetic variants affect the response to glucagon-like peptide 1 (GLP-1) receptor agonists drugs, according to a new large-scale study by the 23andMe Research Institute...
Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
Genetic variants influence how environment affects DNA methylation
Identical twins share the same genetic sequence and much of their early environment, but differences in their epigenetics may reveal how genes and environment interact...