Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
BioNews
163 articles
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Gene therapy vector DNA found integrated into patient's brain tumour
Adeno-associated virus gene therapy vector DNA has been found integrated within tumour tissue in a patient with Hurler syndrome who had been treated years earlier...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Refined CAR-T cell therapy achieves cancer remission without chemotherapy
A new type of CAR-T cell therapy has achieved complete remission in patients with blood cancers, using lower cell doses and without the need for chemotherapy preconditioning...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
In utero stem cell therapy for spina bifida found safe in early trial
The use of stem cell patches to treat fetuses with spina bifida has been shown to be safe following a phase 1 clinical trial...
Nearly 200 children born from sperm of donor with cancer-causing mutation
Sperm from a donor who was unknowingly carrying a cancer-causing mutation has been used to conceive at least 197 children across Europe...
Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
Epigenome editing could improve CAR-T cell cancer therapies
CAR-T cell cancer treatments could be made safer and more durable by reprogramming T cells without altering their DNA, according to new research...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
CRISPR may lead to improvements in cancer immunotherapies
CRISPR/Cas9 has been used to identify genome editing targets that significantly enhance the efficiency of a targeted therapy for myeloma, a type of cancer...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Blocking splicing pathway suppresses aggressive cancer growth
Reducing the activity of a single protein by half can significantly suppress tumour growth across multiple cancer types, according to new research...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Stem cells differentiate in response to physical pressure
Squeezing human stem cells through confined spaces can generate bone-forming cells, according to new research...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Genomics research reveals millions of hidden mutations in childhood cancer
Childhood kidney tumours contain significantly more genetic mutations than previously thought, according to recent research...