Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
BioNews
161 articles
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Hunter syndrome gene therapy approval pathway paused again
The US Food and Drug Administration (FDA) has put a clinical hold on an experimental gene therapy for Hunter syndrome due to nodules being discovered in the spine of five patients who previously received treatment...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Tumour organoid biobank maps gene dependencies in multiple cancers
A comprehensive biobank of patient-derived tumour organoids has been developed to map genes that cancer cells depend on for growth and survival...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Inherited genetics could influence how cancers develop after DNA damage
Inherited genetic differences may help explain why people exposed to the same cancer risk factors, such as smoking and ultraviolet radiation, do not all develop cancer, according to research in mice...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
T cell therapy linked to long-term remissions in children with brain tumours
An experimental autologous T cell therapy has shown encouraging early results in children with aggressive brain tumours...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Genomic test may help some breast cancer patients avoid chemotherapy
Patients diagnosed with breast cancer may be able to safely avoid chemotherapy if a genomic test indicates they are at low risk of their cancer returning, according to findings presented at a major cancer conference...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Abnormal protein activity may contribute to DNA damage in cancer cells
Overproduction of a DNA repair protein called EXO1 can trigger DNA damage and increase chemotherapy sensitivity in human cancer cells, a new study has reported...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Gene therapy vector DNA found integrated into patient's brain tumour
Adeno-associated virus gene therapy vector DNA has been found integrated within tumour tissue in a patient with Hurler syndrome who had been treated years earlier...