PET PET
  • My Account
  • Subscribe
Become a Friend Donate
  • About Us
    • People
    • Press Office
    • Our History
  • Get Involved
    • Become a Friend of PET
    • Volunteer
    • Campaigns
    • Writing Scheme
    • Partnership and Sponsorship
    • Advertise with Us
  • Donate
    • Become a Friend of PET
  • BioNews
    • News
    • Comment
    • Reviews
    • Elsewhere
    • Topics
    • Glossary
    • Newsletters
  • Events
    • Upcoming Events
    • Previous Events
  • Engagement
    • Policy and Projects
      • Resources
    • Education
  • Jobs & Opportunities
  • Contact Us
  • About Us
    • People
    • Press Office
    • Our History
  • Get Involved
    • Become a Friend of PET
    • Volunteer
    • Campaigns
    • Writing Scheme
    • Partnership and Sponsorship
    • Advertise with Us
  • Donate
    • Become a Friend of PET
  • BioNews
    • News
    • Comment
    • Reviews
    • Elsewhere
    • Topics
    • Glossary
    • Newsletters
  • Events
    • Upcoming Events
    • Previous Events
  • Engagement
    • Policy and Projects
      • Resources
    • Education
  • Jobs & Opportunities
  • Contact Us
  • My Account
  • Subscribe
  • Privacy Statement
  • Advertising Policy
  • Thanks and Acknowledgements
PETBioNewsNewsIs '15' the perfect number for IVF success?

BioNews

Is '15' the perfect number for IVF success?

Published 1 November 2012 posted in News and appears in BioNews 607

Author

Dr Rosie Morley

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.

A study of over 400,000 IVF treatment cycles in the UK has found a 'strong association' between the number of eggs retrieved prior to a woman undergoing IVF and live birth rate. The findings suggest that chances of a live birth increased with the number of eggs collected up to the number of 15, after which it began to decline....

A study of over 400,000 IVF treatment cycles in the UK has found a 'strong association' between the number of eggs retrieved prior to a woman undergoing IVF and live birth rate. The findings suggest that chances of a live birth increased with the number of eggs collected up to the number of 15, after which it began to decline.

'This is the first study to look at the association between the number of eggs and live births. Some smaller studies have reported previously on the association between egg numbers and pregnancy rates, but not live births', said Dr Arri Coomarasamy, one of the authors of the study.

The study analysed data obtained by the UK's Human Fertilisation and Embryology Authority (HFEA) on IVF cycles that took place in the UK between April 1991 and June 2008. It found the more eggs retrieved the greater the live birth rate, up to between 15-20 eggs, where there was no change. After 20 eggs the live birth rate declined.

Normally, women produce only one egg at a time. To increase the chance of implanting a viable embryo, women undergoing IVF take hormones to stimulate their ovaries to produce more eggs. Dr Coomarasamy said: 'Mild stimulation protocols aim to retrieve less than six to eight eggs; a standard stimulation should aim for 10-15 eggs, and we believe this is what is associated with the best IVF outcomes; when the egg number exceeds 20, the risk of ovarian hyperstimulation syndrome (OHSS) becomes high'.

The researchers also created a graph describing the relationship between women's age, the number of eggs retrieved and the predicted live birth rate. This, combined with already existing techniques such as anti-mullerian hormone (AMH) testing and antral follicle count (AFC) which are used for predicting how many eggs will be retrieved after ovarian stimulation, could be useful for helping doctors to predict a woman’s IVF success rate.

The study was published in the journal Human Reproduction.

Related Articles

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
13 December 2013 • 1 minute read

Every step of IVF affected by woman's age

by Dr Kimberley Bryon-Dodd

The first study to break down IVF failure rates for each treatment stage across different age groups has found that after the age of 37 the chance of a woman becoming pregnant through IVF rapidly declines...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
12 November 2012 • 1 minute read

Hormone levels and IVF success, new links found

by Dr Kimberley Bryon-Dodd

US researchers have found a link between an ovarian hormone called anti-mullerian hormone (AMH) and IVF success. The findings suggest AMH testing could help clinicians tailor doses of ovary-stimulating drugs to improve women's egg production and likelihood of pregnancy...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
12 November 2012 • 1 minute read

Experts say '15' may not be the perfect number for IVF success after all

by Dr Rosie Morley

A US fertility clinic has issued a press release warning against simplistic interpretations of a recent report on IVF success rates...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
1 November 2012 • 2 minutes read

New genetic test may help to improve IVF success

by Dr Rosie Morley

Multiple genetic tests have been performed on a single embryo for almost the first time, according to US researchers. The researchers from John Hopkins School of Medicine say their technique for making copies of an embryo's DNA can improve IVF success rates...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
31 October 2012 • 2 minutes read

Can reducing stress really improve IVF success rates?

by Dr Kimberley Bryon-Dodd

Women who attended a mind and body course shortly before undergoing IVF demonstrated increased pregnancy rates compared with those that did not, a US study has found. The findings suggest that stress relief may increase the likelihood of becoming pregnant from IVF....

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
31 October 2012 • 2 minutes read

Lower IVF success in women of African origin linked to autoimmunity, suggests study

by Mehmet Fidanboylu

A genetic predisposition towards autoimmune disease may be associated with lower pregnancy rates in IVF, a US study suggests. The findings offer a possible explanation for differences in IVF treatment outcomes between different ethnic groups....

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
17 October 2012 • 1 minute read

Keep trying for IVF success, new study suggests

by Leo Perfect

Researchers from the University of Western Australia have published a study suggesting IVF effectiveness could be improved by undergoing more cycles....

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
11 October 2012 • 1 minute read

Stress doesn't affect IVF success, study finds

by Dr Lucy Freem

Stress levels are unlikely to affect whether or not a woman becomes pregnant following fertility treatment despite anecdotal reports, a review suggests....

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
26 September 2012 • 2 minutes read

Online tool for predicting IVF success launched

by Dr Gabby Samuel

Researchers have developed a calculator that they claim can be used to provide people who are having fertility problems with an assessment of the likelihood of having a successful outcome following IVF...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
26 September 2012 • 1 minute read

BPA can affect egg quality, study claims

by Dr Lux Fatimathas

US researchers have shown a correlation between human egg quality and blood bisphenol A (BPA) levels. In a small-scale study women with higher blood BPA levels showed...

Leave a Reply Cancel reply

You must be logged in to post a comment.

« Multiple birth linked to longevity, study claims

Data-Label The UK's Leading Supplier Of Medical Labels & Asset Labels

RetiringDentist.co.uk The UK's Leading M&A Company.
easyfundraising
amazon

This month in BioNews

  • Popular
  • Recent
13 June 2022 • 2 minutes read

Drop in diversity of blood stem cells leads to old-age health issues

5 July 2022 • 1 minute read

No difference between fresh and frozen sperm for IUI

4 July 2022 • 2 minutes read

Shorter IVF protocol reduces risk of OHSS

4 July 2022 • 2 minutes read

USA scrambles to understand implications of Roe v Wade on fertility industry

4 July 2022 • 2 minutes read

Genetic and epigenetic causes of IVF embryo arrest discovered

4 July 2022 • 2 minutes read

Dutch donor-conceived people seek answers

Subscribe to BioNews and other PET updates for free.

Subscribe
  • Twitter
  • Facebook
  • Instagram
  • LinkedIn
  • YouTube
  • RSS
Wellcome
Website redevelopment supported by Wellcome.

Website by Impact Media Impact Media

  • Privacy Statement
  • Advertising Policy
  • Thanks and Acknowledgements

© 1992 - 2022 Progress Educational Trust. All rights reserved.

Limited company registered in England and Wales no 07405980 • Registered charity no 1139856

Subscribe to BioNews and other PET updates for free.

Subscribe
PET PET

PET is an independent charity that improves choices for people affected by infertility and genetic conditions.

  • Twitter
  • Facebook
  • Instagram
  • LinkedIn
  • YouTube
  • RSS
Wellcome
Website redevelopment supported by Wellcome.

Navigation

  • About Us
  • Get Involved
  • Donate
  • BioNews
  • Events
  • Engagement
  • Jobs & Opportunities
  • Contact Us

BioNews

  • News
  • Comment
  • Reviews
  • Elsewhere
  • Topics
  • Glossary
  • Newsletters

Other

  • My Account
  • Subscribe

Website by Impact Media Impact Media

  • Privacy Statement
  • Advertising Policy
  • Thanks and Acknowledgements

© 1992 - 2022 Progress Educational Trust. All rights reserved.

Limited company registered in England and Wales no 07405980 • Registered charity no 1139856