Technology Network Genomics Research reports that scientists at the University of California, Berkeley, have wrapped the Cas9 editing proteins and guide RNAs in a membrane bubble with the ability to target specific types of blood cells.
This 'bubble' delivery system could allow cells to undergo genome editing while in the body and would eliminate the need to obliterate patients' bone marrow and immune system before giving them edited blood cells.
Their findings are published in Nature Biotechnology.
