CRISPR Associated Proteins are enzymes that associate with CRISPR RNAs to bind to and alter DNA or RNA target sequences.
Cas enzymes originate in bacteria and as such a wide variety of types exist. Some are used for genome editing or editing RNA.
There are also versions that have been altered in the lab to perform specific tasks. Common examples include Cas9 which makes a double-stranded break in a target DNA sequence, and Cas13 which targets RNA.
Base editing can efficiently alter the DNA of human embryos, but it can also result in unintended genomic changes....
A new CRISPR-based approach has been designed to selectively eliminate human cells with disease-causing genes in vitro...
The physical shape of DNA in a cell influences the rate of unintended, off-target effects of CRISPR/Cas9 genome editing...
A new genome editing approach has been shown to safely and efficiently remove the source of transthyretin amyloidosis in mice, demonstrating greater therapeutic opportunities for genome editing...
Side effects of viral-delivered gene therapies have been elucidated using human stem-cell derived kidney organoids...
A patient with type 1 diabetes has been successfully treated with donor pancreas cells modified to evade the immune system...
A genome editing approach has been used to correct a disease-causing genetic variation in people, for the first time...
A novel way to control CRISPR genome editing using focused ultrasound has been discovered...
Subscribe for free to what PET does best – informing you of the latest in fertility, genomics and embryo research.
