CRISPR Associated Proteins are enzymes that associate with CRISPR RNAs to bind to and alter DNA or RNA target sequences.
Cas enzymes originate in bacteria and as such a wide variety of types exist. Some are used for genome editing or editing RNA.
There are also versions that have been altered in the lab to perform specific tasks. Common examples include Cas9 which makes a double-stranded break in a target DNA sequence, and Cas13 which targets RNA.
The safety and efficiency of CRISPR-based genome editing may be improved by using an enzyme that cuts just one strand of DNA instead of both...
Full-term mouse offspring were derived from single unfertilised eggs using targeted CRISPR/Cas9 epigenome editing...
The first team to use CRISPR to edit a disease-causing gene in humans has found the effects are persistent up to a year later...
A hidden component of the CRISPR/Cas3 genome editing system, which is essential for it to work, has been discovered by scientists...
Researchers have developed several new CRISPR techniques to modify the genomes of bacterial populations on a large scale...
Researchers looking for evolutionary ancestors of enzymes used in the CRISPR genome-editing approach have uncovered over one million potential genome-editing enzymes...
Potential applications of CRISPR could be broadened by a new miniature version of the genome editing approach...
Genome editing is a group of approaches that enable scientists to add, remove or alter selected DNA sequences at particular locations in the genome...
CRISPR-based diagnostic test has been designed that can be used at home to detect SARS-CoV-2 and multiple variants from saliva within one hour...
Using CRISPR/Cas9 genome editing in human embryos may introduce 'on-target' errors...
BioNews, published by the Progress Educational Trust (PET), provides news and comment on genetics, assisted conception, embryo/stem cell research and related areas.
