Two research teams have used different DNA-recording technologies to trace cell lineages in developing mouse embryos...
The discovery of a new gene-targeting system used by viruses to fend off competitors gives a glimpse into the possible evolutionary origin of CRISPR, and may offer new opportunities for genome editing technologies...
Dr Tom Turner explores Professor Jennifer Doudna's reflections on the discovery of CRISPR and the future of genome editing in this conversation, which examines one of the most transformative advances in modern biology…
Human brain organoids have been kept in culture for more than five years, extending the period over which these models of human brain development have previously been maintained...
A six-year-old girl has died following an experimental genome editing treatment, prompting an investigation into the clinical trial by the university involved...
A gut cell atlas built from patient biopsies reveals gene activity changes across gut cell types in Crohn's disease...
Adults who use e-cigarettes showed differences in gene expression compared with non-users, with many of these changes varying according to the flavour and type of vaping device used...
A new CRISPR-based approach has been designed to selectively eliminate human cells with disease-causing genes in vitro...
A newly described neurodevelopmental disorder has been linked to changes in a small noncoding gene...
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