The use of preimplantation genetic testing for polygenic risk (PGT-P) by some fertility clinics in the US, has been criticised by a number of experts in the UK, the Telegraph reported.
Sarah Norcross, director of PET (Progress Educational Trust), the charity that publishes BioNews, told the newspaper: 'These scores don't tell you anything concrete or reliable about the presence or absence of a specific gene variant... The resulting data just doesn't give you the kind of certainty that you need to meaningfully select embryos.'
Pointing out that the genomes of embryos from the same two parents 'are unlikely to differ substantially enough' for tests to provide much information, she added: 'These are just some of the reasons why PET – along with many other organisations – thinks it is wrong to offer PGT-P to patients.'
