DNA damage during chemotherapy can trigger treatment resistance
Chemotherapy can produce a rogue response that eventually leads to tumours becoming resistant to treatment, scientists have found...
Dr Caroline Hirst was previously a Volunteer Writer at BioNews, and a Research Fellow in the Neural Development Unit at University College London's Institute of Child Health. Her research to date has focused on developmental genetics, and her current research - which is funded by the Medical Research Council, and conducted under the supervision of Professor Andrew Copp and Dr Nicholas Greene - focuses on the pathogenesis of neural tube defects in mammals. In particular, she is researching the molecular and cellular role of Grainyhead-like genes, and their influence on neural tube closure in early embryonic mouse development. Previously, she studied Human Genetics at the University of Nottingham, where she went on to obtain a PhD conducting research into the key genetic signals involved in neural fate choice during early zebrafish development.
Chemotherapy can produce a rogue response that eventually leads to tumours becoming resistant to treatment, scientists have found...
Skin cells from volunteers with Down's syndrome have been turned into brain cells in order to provide a new model for researchers to study Alzheimer's disease...
Women receiving fertility treatment are more likely to become pregnant if they take multivitamin supplements, reports a UK pilot study...
Tissue engineers from the UK have, for the first time, developed an artificial fetal membrane from human stem cells to be used as a ‘repair patch' to prevent premature births...
UK scientists are launching a global clinical trial to test the potential and safety of stem cells to treat multiple sclerosis (MS)...
Scientists have, for the first time, successfully treated a blood disorder by repairing errors in the DNA of a living animal. Researchers from The Children’s Hospital of Philadelphia, together with California-based Sangamo BioSciences, have applied an innovative genome editing technique to treat haemophilia B, which affects around one in 30,000 boys and men...
Researchers from Johns Hopkins University, USA, have found a link between female infertility and genetic variation in a gene regulating cholesterol uptake...
BioNews, published by the Progress Educational Trust (PET), provides news and comment on genetics, assisted conception, embryo/stem cell research and related areas.