Dr Will Fletcher was previously a Volunteer Writer at BioNews, having originally joined the publication under the auspices of its writing scheme. He obtained his PhD from University College London (UCL)'s Research Department of Genetics, Evolution and Environment, where his research focused on Computational Statistics in Molecular Phylogenetics and where he developed a software application for biological sequence simulation called INDELible. He is also a Quantitative Analyst at the football betting consultancy Smartodds, and he is a former Engineering and Physical Sciences Research Council supported Fellow at the Parliamentary Office of Science and Technology, where he conducted research into edemocracy. Previously, he studied Mathematics at UCL, then went on to obtain an MSc in Theoretical Physics from King's College London and an MRes in Modelling Biological Complexity from UCL's Centre for Mathematics and Physics in the Life Sciences and Experimental Biology. He is particularly interested in cutting-edge genetic research, and the advances in medical treatment that it makes possible.
Neural fetal stem cell injections, administered to a boy in Russia in an attempt to treat a rare genetic condition, have caused benign brain tumours to grow. This is the first documented example of such a complication in a human, although there have been reports of tumours...
Third-generation 'single-molecule' technology has been used for the first time to read a human genome sequence. Professor Stephen Quake, from Stanford University, California, US, is only the eighth person whose genome has been published since the first breakthroughs were made in 2000. When this latest generation of technology is perfected the hope is that it will bring us one step closer to ‘the $1,000 genome' that will open the door to personalised medical treatme...
The genetic material in sperm has far greater influence over the development of a fertilised egg than was previously imagined. A new joint study from the Huntsman Cancer Institute (HCI) and the IVF and andrology lab at the University of Utah, US, has revealed that the father's sperm passes along a previously unrecognised set of instructions that probably tell the developing embryo which specific genes should be turned on and off. The findings, which could lead to new diagnostic tests to help ...
Scientists have discovered a gene mutation that can cause children to be born deaf...
A recent study has lent more weight to the view that 'Junk DNA' may be anything but junk. A joint effort by the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany and Stanford University, California, US, has uncovered large differences between the non-coding DNA of different individuals, which may be associated with differing levels of disease risk and other traits too...
Sequencing a patient's genome to find the genetic cause of their inherited disease has finally been proven to be a viable clinical approach in two recent independent studies. For some time gene sequencing has been heralded as ushering in a new era of medicine. However, until now, only around 10 people in the world had had their personal genomes sequenced in full, and all of these were healthy people. Now, in the ten years since the first full genome was sequenced (at a cost of ...
Women who eat too much fibre may ovulate less and have lower oestrogen levels, according to a recent study...
A commercial product claiming to be the first to make use of induced pluripotent stem cells (iPS cells) has been launched, albeit not a product that can be directly used on humans. Cellular Dynamics International (CDI), a biotech company based in Madison, Wisconsin, US, has recently announced that it has released human heart cells derived from iPS cells for commercial use. CDI intends its trademarked iCell Cardiomyocytes to be used by pharmaceutical companies to aid in the drug...
In the future children could be given 'personalised' vaccine shots if they are found to be in the genetic minority pf people who don't benefit fully from standard forms of a vaccine. Not everyone produces the same amount of disease specific antibodies in response to a vaccine, meaning that a vaccination will not protect some people when they later come into contact with that disease. However, scientists from the National Institute for Occupational Safety and Health (NIOSH), Morgantown, West V...
The first genetic historical map of the Han Chinese has been published in the American Journal of Human Genetics by scientists from the Genome Institute of Singapore (GIS). Based on genome-wide variation in 8,200 individuals, the new map has provided many insights into the evolutionary history and population structure of the Han Chinese which is the largest ethnic population in the world. The map is of great importance as it has helped uncover subtle differences in the genetic ...
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