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PETBioNewsGlossaryDNA methylation

BioNews

DNA methylation

A biochemical process in which a DNA molecule is modified by the addition of methyl chemical groups at selected locations. It is important in the control of gene expression and embryonic development in higher organisms.

66 articles
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
23 May 2022 • 1 minute read

Sperm epigenetics linked to likelihood of pregnancy

by Daniel Jacobson

A new method for determining the 'biological age' of sperm may be a useful predictor of pregnancy success...

Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
CC BY-SA 3.0
Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
News
8 October 2021 • 2 minutes read

Depression during pregnancy linked to epigenetic changes in the placenta

by Joanne Delange

Depression during pregnancy has been linked to placental gene modifications according to a study conducted by NIH researchers...

Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
CC BY-SA 3.0
Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
News
18 June 2021 • 2 minutes read

Epigenetics study reveals how genes are regulated in dementia

by Dr Emma Green and 1 others

A study has identified 84 new genes linked to Alzheimer's disease by combining and analysing data from over 1400 people...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
15 January 2021 • 2 minutes read

Epigenetic changes in sperm may predict autism in children

by Joanne Delange

Biomarkers in human sperm have been discovered that may specify whether a father is likely to have a child with autism...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
13 November 2020 • 2 minutes read

Epigenetic risks during pregnancy reduced with lifestyle intervention

by Eleanor Mackle

Mothers with obesity and gestational diabetes may be able to reduce the risk of epigenetic changes to their baby's DNA by making dietary and lifestyle changes during pregnancy...

Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
CC BY-SA 3.0
Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
News
15 May 2020 • 2 minutes read

First epigenetic study in 3D human cancer cells

by Charlott Repschläger

Researchers have, for the first time, characterised the epigenetic profile of tumour organoids and made their results available in public databases...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
6 March 2020 • 2 minutes read

Premature birth may have long-term epigenetic effects

by Jonathan Bestwick

Researchers have found that children's DNA expression can be altered by length of pregnancy...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
5 September 2019 • 2 minutes read

IVF temporarily changes babies' epigenetics

by Dr Rachel Montgomery

A new study has found that children born from assisted reproductive technologies have different epigenetic patterns to those born through natural conception - but that these differences vanish by adulthood...

Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
CC BY-SA 3.0
Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
News
22 February 2019 • 2 minutes read

Child obesity starts with epigenetic changes in womb

by Dr Rachel Montgomery

The risk of being obese as a child can be predicted by DNA modifications that arise while in the womb, and may be influenced by the mother's diet, suggests a new study...

Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
CC BY-SA 3.0
Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
News
19 October 2018 • 2 minutes read

Epigenetic test sorts fatal from manageable prostate cancer

by Isobel Steer

Researchers have identified a DNA methylation signature that can identify aggressive prostate cancer, with up to 92 percent accuracy...

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