Gene expression is the process of converting the information contained in a gene into the gene product. The DNA of the gene is first transcribed into RNA, which is then either translated into a protein or remains as an RNA molecule. The expression level of a particular gene can be turned ’up’ or ‘down’ in different cells at different times, as required.
New research using mice may reveal how smoking affects reproductive health via different mechanisms in men and women...
A genetic variant linked to Alzheimer's disease impairs the production of the fatty layer that insulates neurons by disrupting an important signalling pathway...
Researchers have turned an 80-year-old's blood precursor cells into neural stem cells, resetting the cells' 'biological age' in the process...
From light-sensitive, single-celled algae to using lasers to trigger mouse whisker movements, the 2026 Nobel Prize in Physiology or Medicine recognises the discovery of light-gated ion channels and their applications in optogenetics to study brain function...
Chronic cigarette smoke exposure may change lung stem cells in ways that influence which types of lung cancer develop when cancer-driving genetic alterations occur...
A primate-specific gene known as BC200 has been found to have 'jumped' into a human virus from the pox family...
A new AI-powered database predicts the effects of single-nucleotide changes in any of the three billion bases in human DNA...
Dr Tom Turner explores Professor Jennifer Doudna's reflections on the discovery of CRISPR and the future of genome editing in this conversation, which examines one of the most transformative advances in modern biology…
The role of PLCG2 – a gene linked to Alzheimer's disease – in brain health may be broader than previously thought, a new study suggests...
Profiling DNA interactions in a rare immune cell type provides a route from disease-associated variants to candidate genes in Crohn's disease...
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