Gene expression is the process of converting the information contained in a gene into the gene product. The DNA of the gene is first transcribed into RNA, which is then either translated into a protein or remains as an RNA molecule. The expression level of a particular gene can be turned ’up’ or ‘down’ in different cells at different times, as required.
A new AI-powered database predicts the effects of single-nucleotide changes in any of the three billion bases in human DNA...
Dr Tom Turner explores Professor Jennifer Doudna's reflections on the discovery of CRISPR and the future of genome editing in this conversation, which examines one of the most transformative advances in modern biology…
The role of PLCG2 – a gene linked to Alzheimer's disease – in brain health may be broader than previously thought, a new study suggests...
Profiling DNA interactions in a rare immune cell type provides a route from disease-associated variants to candidate genes in Crohn's disease...
Chronic inflammation and premature ageing of the ovaries have been associated with the loss of a specific gene in mice...
A synthetic cell created entirely from non-living chemical components can grow, replicate its genetic material and divide, completing the typical life cycle of a cell in the laboratory...
News from ESHRE – air pollution is associated with epigenetic changes in sperm DNA…
Neurons can experience and repair DNA breaks during healthy brain development, particularly as they migrate through tightly packed regions of the developing brain...
Professor Lorenz Studer and Tyler Lamb argue that existing ethical oversight enables responsible human embryonic stem cell research, and that continued NIH support is vital for regenerative medicine, disease modelling and new therapies...
A gut cell atlas built from patient biopsies reveals gene activity changes across gut cell types in Crohn's disease...
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