Gene expression is the process of converting the information contained in a gene into the gene product. The DNA of the gene is first transcribed into RNA, which is then either translated into a protein or remains as an RNA molecule. The expression level of a particular gene can be turned ’up’ or ‘down’ in different cells at different times, as required.
More than 13,000 genetic variants that alter gene activity and may contribute to complex diseases have been identified...
Changes in the expression of 556 genes within uterine gland cells may explain why embryo implantation can fail repeatedly in some fertility patients...
Caffeine reversibly controlled gene expression in a human cell line when linked to an engineered protein system...
A novel artificial intelligence tool has been developed to predict the molecular and regulatory effects of genetic variants relevant to health and disease...
CRISPR/Cas9 genome editing has been used in mice to investigate two key genes' roles in male fertility and sperm production...
Over 31,000 new transcripts found in blood cells from non-European populations are absent from current human gene reference maps...
The 3D structure of the human genome has been mapped at the level of individual bases, defining complex structures which control how DNA functions within the cell...
CAR-T cell cancer treatments could be made safer and more durable by reprogramming T cells without altering their DNA, according to new research...
The largest gene-expression study in African Americans with Alzheimer's disease reveals overexpression of a gene also implicated in those with white European ancestry...
Changes in ovarian tissue, not just egg quantity and quality, may play a role in the decline of female fertility with age, new research suggests...
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