New method refines CRISPR base editing
Splitting and reconstituting the enzymes used in the base editing method of genome editing may make more controlled changes possible...
BioNews
Enzyme
Proteins produced by a living organism which act to bring about, or increase the rate of, a specific biochemical reaction.
301 articles
Brain inflammation caused by air pollution reduces sperm count in mice
Inflammation of certain neurons in the hypothalamus region of the brain is responsible for reduced sperm counts in male mice exposed to high-levels of air pollution, scientists have shown...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
NICE recommends new RNAi therapy for porphyria patients
A gene silencing treatment for a rare, but debilitating genetic disorder has been recommended for NHS use by the National Institute for Health and Care Excellence....
Lack of Prss50 genes severely affects male fertility in mouse model
An gene previously unknown to have a role in fertility has been found to be essential for healthy sperm...
Genetic variant increases Alzheimer's and severe COVID-19 risk
A gene variant has been identified that is linked to the development of both Alzheimer's and severe COVID-19, new research has found...
Gene that determines severity of COVID-19 discovered
Individuals with a specific version of the OAS1 gene have natural antiviral defences against SARS-CoV-2, resulting in less severe COVID-19 disease...
Artificial mitochondria generate energy and save damaged cells
Artificial mitochondria capable of releasing energy, which can be used to repair damaged cells, have been created, claim a team of researchers...
Over one million potential genome-editing enzymes discovered in microbes
Researchers looking for evolutionary ancestors of enzymes used in the CRISPR genome-editing approach have uncovered over one million potential genome-editing enzymes...
Research sheds light on the role of ACE2 in ovulation
Angiotensin converting enzyme 2 is involved in vital cyclic ovarian functions and thus COVID-19 may impact female reproductive health...
CRISPR-based COVID-19 diagnostic detects variants
CRISPR-based diagnostic test has been designed that can be used at home to detect SARS-CoV-2 and multiple variants from saliva within one hour...