Second Chinese team create genetically modified human embryos
A second team in China report that they have created genetically modified human embryos, in an attempt to make them resistant to HIV, using the genome-editing technique CRISPR/Cas9...
BioNews
Genome editing
Making deliberate alterations to the DNA sequence at targeted locations in the genome. This can include deleting, inserting or replacing sections of DNA. Several approaches can be used to achieve these changes including zinc finger nucleases (ZFNs), TALENs, CRISPR/Cas and base editing.
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Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
HIV edited out of T cells using CRISPR
Scientists have used the CRISPR genome-editing technique to remove HIV from the DNA of infected T cells and prevent reinfection...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Ancient viruses buried in our genomes help to fight off new ones
Ancient viral DNA could be helping our immune system fight off infections from modern viruses and other pathogens...
CRISPR-like immune system found in giant virus
Researchers have found that mimiviruses, a class of giant viruses, have an immune system reminiscent of the CRISPR system used by bacteria to evade infection...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Radio Review: Editing Life
Professor Matthew Cobb investigates some of the implications of the groundbreaking CRISPR genome-editing technology in this BBC Radio 4 documentary...
Mitochondrial replacement techniques: US-style
The US NAS has published a report on the ethical, social and policy considerations relating to mitochondrial replacement techniques. The recommendation that has inevitably attracted most attention, however, is that only male embryos should be transferred, an approach that was considered but rejected in the UK...
The distracting genome
Last week the front pages and airwaves filled with well-written, balanced articles about a significant development in UK embryo research. There was, however, something missing: a story...
Video Review: Talking Biopolitics — A conversation with Paul Knoepfler and Nathaniel Comfort
An author and a science historian host an online discussion on the promise and perils of the 'science of designer babies'...
CRISPR corrects mutation that causes blindness
Researchers have used the CRISPR/Cas9 genome-editing technique to correct a genetic mutation that causes blindness...
Germline in the sand: The ethics and law of engineering the embryo
We report from the fourth session of annual conference of the Progress Educational Trust, titled 'Germline in the Sand: The Ethics and Law of Engineering the Embryo', which discussed the ethics of human embryo genome editing...