Mitochondrial diseases are soon to be brought to the attention of the general public, as the Government seeks to gauge the attitude of the nation towards a ground-breaking IVF treatment that could prevent these conditions being passed from mother to child...
Preimplantation genetic screening (PGS) for aneuploidy was first reported by Verlinsky et al (1995) and Munne et al (1995). Both of these initial studies analysed polar bodies. The aim of the technique is to help determine the best IVF embryo for transfer on the grounds of the polar body or embryo's chromosomes, by performing biopsy and analysis of the chromosomes using fluorescent in situ hybridisation (FISH). There have been hundreds of papers on the use of PGS. It is well known that for pa...
Embryo selection following cleavage stage embryo biopsy and chromosome analysis to identify aneuploid embryos (those which have an abnormal number of chromosomes) in every couple having IVF/ICSI or all women of advanced maternal age is rightly considered by most clinics to be too invasive and potentially damaging for routine...
Make a habit of two things - to help, or at least to do no harm' (Attr Hippokrates of Kos). The principle of preimplantation testing for sporadic chromosome aneuploidy (preimplantation genetic screening, PGS) to improve the reproductive efficiency of assisted conception for couples at increased risk is a sound one. It...
Ten years since the first reports of preimplantation genetic diagnosis for abnormal chromosome number, or aneuploidy, (now commonly known as PGS - preimplantation genetic screening), we are experiencing a prejudicial mistrust of a clinical approach that is generally accepted to be scientifically and clinically sound. Opponents of PGS frequently criticise its...
A team of Japanese and US researchers has managed to create transgenic zebrafish, using genetically-modified sperm grown in the laboratory. Researchers at the Fukui Prefectural University in Obama, Japan and the US National Human Genome Research Institute (NHGRI), say their findings have implications for a wide range of research areas...
The European Society of Human Reproduction and Embryology (ESHRE) held their annual meeting in Tours last week. The European Society of Human Genetics (ESHG) held theirs in Geneva at the end of May...
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