Unintended changes to a genome, away from the desired target site, which occur as a consequence of genome editing.
A new genome editing approach has been shown to safely and efficiently remove the source of transthyretin amyloidosis in mice, demonstrating greater therapeutic opportunities for genome editing...
CRISPR-based genome editing has been used to overcome chemotherapy resistance in lung tumours by disabling a tumour-specific mutation...
A new multipurpose genome editing approach could address around a third of rare genetic diseases...
A new mRNA-based therapy has restored fertility in mice that were unable to produce sperm...
An artificial intelligence tool for helping to create CRISPR workflows can enable beginners to design successful experiments in a single attempt...
A precision genome editing approach has successfully corrected harmful mutations in mitochondrial DNA, offering new hope for treating currently incurable mitochondrial diseases...
Circular DNA existing outside chromosomes can drive cancer growth and is a potential drug target, according to three papers published this week in Nature...
A novel gene therapy approach that directly targets immune cells within a patient's body has been trialled in a B-cell cancer patient...
A podcast series to accompany the film 'Make People Better' gives unique insights into the controversial creation of genome-edited babies by Dr He Jiankui...
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