Unintended changes to a genome, away from the desired target site, which occur as a consequence of genome editing.
Circular DNA existing outside chromosomes can drive cancer growth and is a potential drug target, according to three papers published this week in Nature...
A novel gene therapy approach that directly targets immune cells within a patient's body has been trialled in a B-cell cancer patient...
A podcast series to accompany the film 'Make People Better' gives unique insights into the controversial creation of genome-edited babies by Dr He Jiankui...
A type of genome editing capable of replacing entire genes in the human genome could potentially be used to treat a wide variety of genetic conditions...
Dr Sayyed Mohamed Muhsin and Dr Alexis Heng Boon Chin give an ethical analysis of germline genome editing to prevent genetic diseases based on Islamic legal maxims (Qawaid Fiqhiyyah)...
RNA-based vaccines for COVID-19 can be misread by the body, producing harmless off-target proteins, according to new research...
A gene therapy treatment for sickle cell disease has led to a build-up of cells with genetic mutations that make them grow faster, increasing blood-cancer risk, researchers revealed...
CRISPR/Cas9 genome editing can result in the unintended deletion of a region associated with cancer...
A CRISPR-based treatment for sickle cell disease is one step closer to approval after an advisory committee for the US Food and Drug Administration met to review its safety...
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