Discounted IVF drugs now available via TrumpRx website
US President Donald Trump's anticipated drug-discount programme TrumpRx is now live, and offers reductions on a range of prescription medications, including some widely-used IVF drugs...
News
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Paternal radiation exposure linked to DNA mutations in children
The children of men exposed to radiation following the Chernobyl nuclear reactor incident in 1986 show specific patterns of DNA mutations, providing evidence that radiation-induced changes in sperm can affect offspring...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Regulatory signals in blood stem cells stop leukaemia development
A receptor on the surface of blood stem cells has been found to regulate cell growth, raising the possibility that activating it could offer a new therapeutic strategy for acute myeloid leukaemia...
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
More than 500 genes associated with uterine receptivity
Changes in the expression of 556 genes within uterine gland cells may explain why embryo implantation can fail repeatedly in some fertility patients...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
First cell-level gene maps created for Alzheimer's disease
The first cell-type-specific maps of the brain during Alzheimer's disease have been created, revealing which genes may actively drive the disease rather than simply change in response to damage...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Personalised psoriasis treatments – insights from AI
The severity of psoriasis can be linked to genes, new research using machine learning suggests, supporting the possibility of more tailored treatments...
Reviews
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
Podcast Review: Primary Care Knowledge Boost – Assisted conception
Dr Fitzgerald urges GPs to give frank advice on fertility, emphasising early referral, managing health, reducing stress, and the impact of female age. She stresses that women need full information to make informed choices, even when the news about subfertility is difficult...
Comment
Why did the High Court strip a transgender father of legal parenthood?
by Natalie Gamble
The High Court has ruled that because a man has a gender recognition certificate, he cannot be recognised as legal parent. Natalie Gamble explains why this judgment has profound implications for transgender parents, fertility clinics and the law more broadly...
High Court upholds patients' rights in embryo and gamete storage case
by Dr Nishat Hyder-Rahman
The court's decision 'offers clarity on matters that are legally and ethically complex as well as emotionally challenging', writes Dr Nishat Hyder-Rahman...
PET Podcast: Polygenic Risk, Polygenic Scores, Polygenic Indices – What Are They? What Should Be Done with Them?
by Sarah Norcross
Bringing you PET events as a podcast. In the 42nd episode of its podcast, PET discusses the science and ethics of PGT-P, with Dr Philip Ball, Dr Emma Meaburn, Dr Dorit Barlevy and Professor Angus Clarke...