Aggressive brain cancer linked to gene fusion
Some cases of glioblastoma - a particularly aggressive form of brain cancer - may be due a genetic mutation where two separate genes fuse into one, scientists report...
An abnormal number of chromosomes, either too few or too many. Nearly all human body cells usually have a set of 46 chromosomes, while egg and sperm cells have 23.
by Zara Mahmoud
Some cases of glioblastoma - a particularly aggressive form of brain cancer - may be due a genetic mutation where two separate genes fuse into one, scientists report...
by Ana Pallesen
An IVF test which checks whether embryos carry the correct number of chromosomes could improve the chances of a successful pregnancy, a clinical trial suggests. The test — developed by the biotech company Blue Gnome — is used five days after an egg has been fertilised and helps doctors select which embryos should be implanted during IVF treatment...
A new method of looking for chromosomal abnormalities in embryos can increase the chance of successful IVF implantation, a recent study in the journal Fertilisation In Vitro has shown....
by James Brooks
The third session of the Progress Educational Trust's annual conference 'The Best Possible Start in Life: The Robust and Responsive Embryo' boasted a redoubtable roll-call of eminent clinicians and researchers as speakers...
Two US studies published this week have shed light on how a gene mutation can change the number of chromosomes present in the cells of more than 90 percent of cancers...
European researchers have linked ovarian stimulation in women aged over 35 to increased chromosomal abnormalities. Genetic screening shows that the production of oocytes is disrupted during fertility treatment involving ovarian stimulation...
Multiple genetic tests have been performed on a single embryo for almost the first time, according to US researchers. The researchers from John Hopkins School of Medicine say their technique for making copies of an embryo's DNA can improve IVF success rates...
An embyro screening test could significantly increase IVF success rates, US researchers have found...
Preimplantation genetic screening (PGS) for aneuploidy was first reported by Verlinsky et al (1995) and Munne et al (1995). Both of these initial studies analysed polar bodies. The aim of the technique is to help determine the best IVF embryo for transfer on the grounds of the polar body or embryo's chromosomes, by performing biopsy and analysis of the chromosomes using fluorescent in situ hybridisation (FISH). There have been hundreds of papers on the use of PGS. It is well known that for pa...
UK researchers are planning a trial of a new test for identifying which IVF embryos are most likely to result in a healthy pregnancy. The technique has already been used to achieve seven successful pregnancies in women who had previously been unable to become pregnant with or without IVF....
BioNews, published by the Progress Educational Trust (PET), provides news and comment on genetics, assisted conception, embryo/stem cell research and related areas.