Chromosomes are tightly packaged bundles of DNA, the chemical that encodes genetic information.
Most of the cells in a human body have a set of 46 chromosomes in their nucleus, while egg and sperm cells have only 23.
Separately, each of the mitochondria in each cell of a human body contain their own DNA, in the form of (multiple copies of) a circular chromosome.
Dr Aleksandra Byrska explores why human embryos are prone to chromosomal errors and how these might affect IVF success...
Professor Dusko Ilic remembers his friend and colleague Professor Caroline Ogilvie OBE, whose sharp intellect, generosity and pioneering work in clinical and reproductive genetics touched the lives of patients, families and generations of scientists...
A non-invasive form of PGT-A did not improve pregnancy rates in a clinical trial, but did reduce early miscarriages...
Genetic testing is beginning to identify causes of infertility that were previously unexplained. PET's latest event brought together clinicians and researchers to discuss the opportunities and limitations of reproductive genetics...
People's opinions on using preimplantation genetic testing for non-medical traits do not always reflect the decisions they make about selecting embryos when presented with the results...
PGT-A is widely used to assess the chromosome status of IVF embryos, but how accurately can a biopsy of just a handful of cells predict an embryo's genetic makeup? Dr Desislava Staneva explains why interpreting PGT-A results is more complex than it may first appear...
Scientists have obtained the most complete and accurate sequence of a human diploid reference genome to date, paving the way for advancements in personalised medicine...
Dr Alexis Heng Boon Chin advises against using medical savings intended for old age to fund more fertility treatments...
Adeno-associated virus gene therapy vector DNA has been found integrated within tumour tissue in a patient with Hurler syndrome who had been treated years earlier...
A gene normally active only in reproductive cells may drive genetic instability in aggressive breast cancers, offering a potential new treatment target...
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