Non-invasive PGT-A did not improve pregnancy rates
A non-invasive form of PGT-A did not improve pregnancy rates in a clinical trial, but did reduce early miscarriages...
BioNews
Aneuploidy
An abnormal number of chromosomes, either too few or too many. Nearly all human body cells usually have a set of 46 chromosomes, while egg and sperm cells have 23.
126 articles
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Can PGT-A give us an accurate picture of the genetic content of embryos?
PGT-A is widely used to assess the chromosome status of IVF embryos, but how accurately can a biopsy of just a handful of cells predict an embryo's genetic makeup? Dr Desislava Staneva explains why interpreting PGT-A results is more complex than it may first appear...
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
Expanding use of Singapore's CPF MediSave for IVF will yield diminishing returns
Dr Alexis Heng Boon Chin advises against using medical savings intended for old age to fund more fertility treatments...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Potential new treatment target for triple-negative breast cancer
A gene normally active only in reproductive cells may drive genetic instability in aggressive breast cancers, offering a potential new treatment target...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Why I think PGT-P should be legalised in the UK
Clinical embryologist and fertility clinic founder Dr Cristina Hickman shares her thoughts on preimplantation testing for polygenic traits ...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Gene variants identified that influence the risk of aneuploidy
Variants in maternal genes that increase the risk of aneuploidy have been identified...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
TV Review: Hitler's DNA – Blueprint of a dictator
Hitler's DNA has been identified and sequenced for the first time. Senior science writer, Dr Matteo Cortese, reviews a BBC programme investigating what the DNA reveals about Hitler's heritage – discussing the technology at its core: polygenic scores...
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
PGT-A as an IVF Add-On: 25 Years of Controversy
The second session of 'What Does Genomics Mean for Fertility Treatment?' – the 2025 Annual Conference of PET – explored controversies surrounding preimplantation genetic testing for aneuploidy...