A tribute to Dr Marta Shahbazi (1985-2026)
The director and deputy director of PET pay tribute to Dr Marta Shahbazi – a prominent and inspiring figure in human embryo research, who was killed in last week's rail collision in Spain...
BioNews
Aneuploidy
An abnormal number of chromosomes, either too few or too many. Nearly all human body cells usually have a set of 46 chromosomes, while egg and sperm cells have 23.
129 articles
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
When our embryos were labelled 'abnormal', we lost the right to choose
Fertility physician, clinical geneticist and bioethicist Dr Shizuko Takahashi questions why PGT-A is being used to limit – rather than inform – patient choices...
Image by K Hardy via the Wellcome Collection. Depicts a human embryo at the blastocyst stage (about six days after fertilisation) 'hatching' out of the zona pellucida.
To err is human: How human embryos rarely get it right
Dr Aleksandra Byrska explores why human embryos are prone to chromosomal errors and how these might affect IVF success...
Non-invasive PGT-A did not improve pregnancy rates
A non-invasive form of PGT-A did not improve pregnancy rates in a clinical trial, but did reduce early miscarriages...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Can PGT-A give us an accurate picture of the genetic content of embryos?
PGT-A is widely used to assess the chromosome status of IVF embryos, but how accurately can a biopsy of just a handful of cells predict an embryo's genetic makeup? Dr Desislava Staneva explains why interpreting PGT-A results is more complex than it may first appear...
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
Expanding use of Singapore's CPF MediSave for IVF will yield diminishing returns
Dr Alexis Heng Boon Chin advises against using medical savings intended for old age to fund more fertility treatments...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Potential new treatment target for triple-negative breast cancer
A gene normally active only in reproductive cells may drive genetic instability in aggressive breast cancers, offering a potential new treatment target...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Why I think PGT-P should be legalised in the UK
Clinical embryologist and fertility clinic founder Dr Cristina Hickman shares her thoughts on preimplantation testing for polygenic traits ...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Gene variants identified that influence the risk of aneuploidy
Variants in maternal genes that increase the risk of aneuploidy have been identified...