Using base editing, a highly precise method of genome editing, scientists have investigated the role of the NANOG gene in human embryos for the first time with this approach...
A CRISPR genome editing therapy provides sustained reductions in 'bad' cholesterol in people with inherited high cholesterol or premature coronary artery disease, an early-stage clinical trial shows...
An artificial intelligence model trained on genomic data can predict disease-causing mutations and design synthetic viruses...
A novel artificial intelligence tool has been developed to predict the molecular and regulatory effects of genetic variants relevant to health and disease...
A detailed integrated map of the human genome's 3D structure over time shows how DNA structure is linked to gene activity...
Eleven people with aggressive T-cell leukaemia have now received a 'base editing' therapy, with seven remaining in remission up to three years after treatment...
An artificial intelligence model has been developed to identify unseen disease-causing genetic variants and rank their severity, according to a new study...
The 3D structure of the human genome has been mapped at the level of individual bases, defining complex structures which control how DNA functions within the cell...
Base editing has been used to correct the mutation causing late-onset Tay-Sachs disease in mice and human cells...
Hundreds are set to receive the first-ever treatment licensed across Great Britain for a rare mitochondrial disease...
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