Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
BioNews
ES (embryonic stem) cell
A type of stem cell found in early embryos, which is capable of developing into all (totipotent) or a wide range of (pluripotent) different body tissues.
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Image by K Hardy via the Wellcome Collection. Depicts a human embryo at the blastocyst stage (about six days after fertilisation) 'hatching' out of the zona pellucida.
Stem-cell-derived monkey embryo models implant in womb
Lab-made model embryos triggered pregnancy responses when placed in the uteruses of female monkeys...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
Errors found in genetic testing and genome editing of embryos
A technique commonly used to amplify minute quantities of DNA to allow genetic testing of early human embryos has been shown to be error-prone. Potentially harmful unintended mutations in genome-edited embryos were also found...
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
Obituary: Professor Brian Lieberman
Professor Daniel Brison recalls the life and work of Professor Brian Lieberman, who founded the world's first publicly-funded IVF unit in Manchester in 1982...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Earliest stages of sex determination explored in stem cell-derived models
Sertoli cells, which are crucial to sperm formation, have been recreated in the lab using pluripotent stem cells, to help study the earliest stages of sex determination...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
First viable mammal with artificial karyotype created
Using a novel technique for chromosome-level genetic engineering, scientists have generated mice with evolutionary genetic changes in the laboratory...
Image by K Hardy via the Wellcome Collection. Depicts a human embryo at the blastocyst stage (about six days after fertilisation) 'hatching' out of the zona pellucida.
Further stages of development observed in mouse embryo models
'Synthetic' model embryos using mouse stem cells and an artificial incubator are the closest a stem-cell-derived embryo model has ever come to resembling a naturally developing embryo in the uterus...
Image by K Hardy via the Wellcome Collection. Depicts a human embryo at the blastocyst stage (about six days after fertilisation) 'hatching' out of the zona pellucida.
Placenta and organ formation observed in mouse embryo models
Researchers in Israel have observed the formation of the placenta, yolk sac and some organs, in embryo models derived entirely from mouse embryonic stem cells...