A type of stem cell found in early embryos, which is capable of developing into all (totipotent) or a wide range of (pluripotent) different body tissues.
A developmental mechanism that restricts nerve regeneration has been identified using neural organoids...
Using base editing, a highly precise method of genome editing, scientists have investigated the role of the NANOG gene in human embryos for the first time with this approach...
Professor Lorenz Studer and Tyler Lamb argue that existing ethical oversight enables responsible human embryonic stem cell research, and that continued NIH support is vital for regenerative medicine, disease modelling and new therapies...
Pausing new submissions to the US National Institutes of Health Human Embryonic Stem Cell Registry could jeopardise treatments and stall decades of research, the International Society for Stem Cell Research has warned....
A refined method has been developed to generate more mature, functional stem-cell-derived pancreatic islets that restore and maintain glucose control in diabetic mice over several months...
Human stem cells edited to evade immune responses survived for five months in mice without triggering rejection...
An early phase clinical trial using induced pluripotent stem cells to treat Parkinson's disease has been approved...
Not all mutations in the CTNNB1 gene — a key cancer driver — are equal, offering insights for personalised cancer treatment...
A large-scale study has unveiled genes essential for early brain development and uncovered the cause of a previously unrecognised neurodevelopmental disorder...
A detailed integrated map of the human genome's 3D structure over time shows how DNA structure is linked to gene activity...
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