Inflammation may cause lasting epigenetic changes in blood stem cells
Blood stem cells can retain a long-term 'memory' of inflammatory events, which may help explain links between ageing, chronic disease and blood cancers...
Blood stem cells can retain a long-term 'memory' of inflammatory events, which may help explain links between ageing, chronic disease and blood cancers...
by Professor Alfonso Martínez Arias and 2 others
Professor Alfonso Martínez Arias, Dr Nicolas Rivron and Dr Naomi Moris set out key recommendations from a foundational framework for research, technological development and regulation in relation to stem-cell-based embryo models...
Epigenetic changes in colon cells caused by colitis can increase susceptibility to developing colorectal cancer in the future...
Identical twins share the same genetic sequence and much of their early environment, but differences in their epigenetics may reveal how genes and environment interact...
The children of men exposed to radiation following the Chernobyl nuclear reactor incident in 1986 show specific patterns of DNA mutations, providing evidence that radiation-induced changes in sperm can affect offspring...
Are we on a path predetermined by the genes we inherit, or are we a product of the social environment with which we interact? Dr Helen Robertson reviews the new book written by sociologist Professor Dalton Conley...
by Yan Lau
CAR-T cell cancer treatments could be made safer and more durable by reprogramming T cells without altering their DNA, according to new research...
Paternal environmental factors, such as diet and gut microbiome, may impact early embryonic development in offspring...
Extremely advanced ageing and poor health are not intrinsically linked, according to a study of the longest-lived supercentenarian...
Nearly 500 'switch-like' genes that are either expressed highly or not at all have been identified from a large-scale study of gene expression from almost one thousand people...
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