The total epigenetic (heritable, non-DNA-sequence based changes to gene expression) modifications that have been added to an organism's genome.
Researchers have turned an 80-year-old's blood precursor cells into neural stem cells, resetting the cells' 'biological age' in the process...
An experimental epigenome-editing therapy has shown a favourable safety profile and increased lean muscle mass in patients with a rare muscular dystrophy in an early-stage trial...
CAR-T cell cancer treatments could be made safer and more durable by reprogramming T cells without altering their DNA, according to new research...
Paternal environmental factors, such as diet and gut microbiome, may impact early embryonic development in offspring...
Extremely advanced ageing and poor health are not intrinsically linked, according to a study of the longest-lived supercentenarian...
A 'multiomic' test could detect biological differences between patients with and without ovarian cancer...
A new method for tracking the lineage and type of different blood cells in humans has shown how ageing changes the make-up of blood...
A programmable stem cell model, with the ability to mimic early stages of mammalian development, has been created using an engineering biology technique...
Gene silencing that causes Prader-Willi syndrome can be efficiently undone by using CRISPR-based epigenome editing, new research has revealed...
A novel way to control CRISPR genome editing using focused ultrasound has been discovered...
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