The addition of one or more nucleotide base pairs into a DNA sequence. Insertions into the coding region of gene (insertion mutations) often stop the gene working.
A new AI model can predict DNA repair following CRISPR-based genome editing, suggesting how to achieve more accurate gene insertions...
Synergistic evidence from two studies published in Nature this week have updated our understanding of the human genome...
A novel gene insertion therapy may be able to cure infants of a rare genetic liver disease...
Insertions of mitochondria DNA are prevalent in our nuclear genome and could be linked to reduced lifespan...
A single dose of a CRISPR-based gene therapy could cure inflammation in people affected by a rare condition that causes life-threatening swelling attacks, according to a new clinical trial...
An improved genome editing method could potentially correct 89 percent of known genetic defects causing disease, US scientists say.
The US Food and Drug Administration (FDA) is taking an active stance against the use of 'do it yourself' gene therapy kits...
A new clinical trial in California marks the first time that genome editing has been used inside the body, rather than on cells such as blood or skin which can be extracted, edited outside the body, and then replaced...
Scientists have developed the genome editing technique known as 'base editing' to turn adenine-thymine base pairs back to guanine-cytosine...
Ancient viral genes have been eliminated from pigs using the genome editing tool CRISPR, according to research...
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