A change in the sequence of DNA. Mutations occurring in genes may prevent them from working properly, which might result in disease (a genetic condition). Mutations occur naturally at a low rate, but can also be induced by radiation and some chemicals.
Combining genome sequencing and cellular reprogramming has allowed researchers to dissect the genetic causes of a recently discovered rapid-ageing disorder...
The most recent PET event took place in Edinburgh and brought together researchers, clinicians and members of the public to examine advances in understanding and treating male infertility...
Epigenetic changes in colon cells caused by colitis can increase susceptibility to developing colorectal cancer in the future...
An artificial intelligence model trained on genomic data can predict disease-causing mutations and design synthetic viruses...
Immune cells within the brain emerge as regulators of puberty onset, maturation of reproductive organs and fertility...
A new gene-targeted drug therapy has shown promise in reducing seizures for patients with a rare genetic childhood epilepsy...
Metabolic disorders can seem forbiddingly complex, but a simplified approach to explaining their biological basis can lead to improved understanding, earlier diagnosis and better management, argues Dr Srividya Sreekantam...
A lipid nanoparticle-based gene therapy for cystic fibrosis restores biological function in a preclinical model...
The children of men exposed to radiation following the Chernobyl nuclear reactor incident in 1986 show specific patterns of DNA mutations, providing evidence that radiation-induced changes in sperm can affect offspring...
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