Gene responsible for lack of sperm identified
Gene variants affecting a single gene have been identified in men who do not produce sperm, giving some insight into genetic control of sperm production...
BioNews
Nucleotide
Nucleotides are the building blocks that make up DNA and RNA molecules. A single nucleotide consists of a nitrogenous base (adenosine, cytosine, guanine, or thymine in DNA), a phosphate group, and a sugar molecule.
32 articles
Sensing changes in DNA structure implicated in disease
A 'chemical nose' can detect the quadruple-stranded DNA associated with diseases such as cancer...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
New rapid genome sequencing to trace COVID-19
A rapid genomics strategy could speed up identification of changes in the genetic code of SARS-CoV-2, helping identify the source of COVID-19 cases...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Podcast Review: Designer Genes (Babbage, The Economist)
When we think of designer babies, we may think of genome-edited babies with their DNA cut and spliced, perhaps using CRISPR...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
New CRISPR tool opens up more of the genome
Researchers have identified a new enzyme to make the genome editing approach, CRISPR, able to target more locations within the genome...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CRISPR genome editing may cause unintended mutations
CRISPR may introduce hundreds of unwanted mutations into the genome, a small study finds...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Human cells have their clock put back
Scientists have developed a technique to lengthen telomeres - the 'caps' on the end of chromosomes that protect DNA - in human cells in the lab, increasing the cells' lifespan...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Event Review: End to End - Telomeres and Ageing
The 2013 Schrödinger Lecture at Imperial College London was delivered by Dr Elizabeth Blackburn, an Australian-American biologist based in California...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Is the SNP consortium philanthropy in action?
The Wellcome Trust is to fund 67% of a two year, $45m (£30m), international project to define some 300,000 DNA sequence variations in the human genome. The remaining funds come from a consortium of ten of the world's leading pharmaceutical companies, who have also agreed to put the newly discovered...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Combined genetic tests could aid autism diagnosis
Scientists have found that two genetic analysis techniques can increase the number of causative mutations found in children with autism spectrum disorder...