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PETBioNewsGlossaryMeiosis

BioNews

Meiosis

The form of cell division by which egg and sperm cells are formed. Unlike normal cell division (mitosis), the number of chromosomes in the resulting cells is half that in the original cells.

42 articles
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
20 June 2022 • 2 minutes read

Whole exome sequencing of mother could predict risk of creating embryos with aneuploidy

by Dr Malena Daich Varela

Variants in three genes have been linked to an increased risk of a woman creating aneuploid embryos while undergoing IVF and used to create a risk score using machine learning...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
Comment
6 December 2021 • 4 minutes read

PGT-A in young, good prognosis populations

by Dr Eric J Forman

A recent large randomised trial published in the New England Journal of Medicine is receiving significant attention with clinicians who are critical of preimplantation genetic testing for aneuploidy (PGT-A) claiming it provides evidence that PGT-A does not improve IVF outcomes and should not be used outside of research settings…

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
Comment
11 October 2021 • 6 minutes read

Advances in Assisted Reproduction: What Can We Expect?

by Annabel Slater

Sarah Norcross, director of the Progress Educational Trust, invited the audience of the event to consider where assisted reproductive technologies stood 55 years ago...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
Reviews
17 September 2021 • 4 minutes read

TV Review: Fighting for Fertility

by Dr Elpida Fragouli

What does it take to make a family when natural conception is difficult or even impossible?..

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
10 September 2021 • 2 minutes read

Functional sperm developed from mouse pluripotent stem cells

by Purvi Shah

Researchers in Japan have successfully demonstrated the development of functional sperm cells that developed into fertile offspring from pluripotent embryonic stem cells, in mice...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
20 August 2021 • 2 minutes read

BRCA2 DNA repair errors implicated in infertility

by Dr Molly Godfrey

BRCA2 mutations may be implicated in infertility, as well as increasing cancer risk, according to new research...

PET BioNews
News
6 August 2021 • 2 minutes read

Gene responsible for lack of sperm identified

by Dr Emma Green

Gene variants affecting a single gene have been identified in men who do not produce sperm, giving some insight into genetic control of sperm production...

Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
CC BY 4.0
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false-coloured cryogenic scanning electron micrograph).
News
16 July 2021 • 2 minutes read

Mouse eggs made from mouse stem cells matured in vitro

by Ruth Retassie

An in vitro gametogenesis (IVG) breakthrough has been achieved as mouse stem cells have been used to create egg cells that have successfully developed into live mice when used in IVF...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
Comment
18 February 2021 • 4 minutes read

Ethics of genetically reconstituting oocytes

by Professor John Loike

In the 16 December issue of Nature, researchers reported that the addition of eight transcription factors to pluripotent stem cells converted them into a primary oocyte-like cell...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
11 December 2020 • 2 minutes read

Human egg cells are often genetically abnormal

by Dr Marieke Bigg

Meiosis, when cells divide to produce eggs, goes wrong much more than previously thought...

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