A reproductive option that was developed for the purpose of avoiding the transmission of mitochondrial disease from mother to child. It involves creating an embryo using nuclear DNA from the prospective parents, and mitochondria (including mitochondrial DNA) from a donor. It is sometimes referred to as MDT (which stands for 'mitochondrial donation treatment') or as MRT (which can stand for either 'mitochondrial replacement therapy' or 'mitochondrial replacement techniques'). There are also specific mitochondrial donation techniques that have their own acronyms.
Clinical embryologist and fertility clinic founder Dr Cristina Hickman shares her thoughts on preimplantation testing for polygenic traits ...
The fifth session of 'What Does Genomics Mean for Fertility Treatment?' – the 2025 Annual Conference of PET – brought together clinical, scientific and ethical perspectives on the relationship between genomics and donor conception...
The sixth session of 'What Does Genomics Mean for Fertility Treatment?' – the 2025 Annual Conference of PET – saw Julia Chain, chair of the HFEA, give a concluding keynote presentation...
An embryo that originally had three pronuclei resulted in a healthy baby after one pronucleus was microsurgically removed...
The latest event from PET brought together voices from the UK and Australia to discuss mitochondrial donation, following recent news of healthy children born in the UK and the passing of Maeve's law in Australia...
Hundreds are set to receive the first-ever treatment licensed across Great Britain for a rare mitochondrial disease...
Following the news that healthy children have been born in the UK following mitochondrial donation IVF, Professor Rachel Bowlby explains why so-called 'three-parent babies' are nothing new...
Dr Andy Greenfield explores what it took to achieve the birth of eight healthy babies with donated mitochondria – not just scientific and technical advances but also ethical inquiry, public and patient engagement, the introduction of new laws and regulations, and the careful establishment of a new clinical pathway...
Eight children have been born in the UK following mitochondrial donation IVF. All eight children have made normal developmental progress, and none of them show any sign of mitochondrial disease...
Mair Crouch, author of the book 'Medical Genetics and Law: An International Perspective', explains why legal professionals need an understanding of genomics (and vice versa)...
Subscribe for free to what PET does best – informing you of the latest in fertility, genomics and embryo research.
