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PETBioNewsGlossarymtDNA (mitochondrial DNA)

BioNews

mtDNA (mitochondrial DNA)

Genetic information located within mitochondria, the cell's energy generators, rather than in the nucleus. Mitochondrial DNA is inherited solely through the maternal line, as sperm contribute no mitochondria to the fertilised egg.

108 articles
Image by Bill Sanderson via the Wellcome Collection, © Wellcome Trust Ltd 1990. Depicts Laocoön and his family (from Greek and Roman mythology) entwined in coils of DNA.
Image by Bill Sanderson via the Wellcome Collection, © Wellcome Trust Ltd 1990. Depicts Laocoön and his family entwined in coils of DNA (based on the figure of Laocoön from Greek and Roman mythology).
Comment
20 June 2022 • 6 minutes read

An adaptive act: How should human fertilisation and embryology legislation respond to scientific and technological change?

by Julian Hitchcock

How responsive is the Human Fertilisation and Embryology Act to the pace of social and technological change? In this comment, Julian Hitchcock contemplates revision of the Act, and how might we optimise its responsiveness to clinical need while upholding standards...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
29 April 2022 • 2 minutes read

TALED genome editing approach targets mitochondrial DNA

by James Moore

An approach which significantly improves the ability to modify mitochondrial DNA in living cells has been developed by scientists in South Korea...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
31 March 2022 • 2 minutes read

Mitochondrial donation becomes legal in Australia

by Michaela Chen

The Australian Senate has passed a bill which will legalise the clinical use of mitochondrial donation by a vote of 37 votes for to 17 against...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
3 December 2021 • 2 minutes read

Mitochondrial donation bill passed in Australia

by Michaela Chen

A bill permitting mitochondrial donation has been passed by the Australian House of Representatives...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
Comment
11 October 2021 • 6 minutes read

Advances in Assisted Reproduction: What Can We Expect?

by Annabel Slater

Sarah Norcross, director of the Progress Educational Trust, invited the audience of the event to consider where assisted reproductive technologies stood 55 years ago...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
Reviews
23 March 2021 • 4 minutes read

TV Review: DNA Family Secrets

by Dr Elpida Fragouli

As a human geneticist I've always been interested in anything DNA-related, whether this is a book, research paper, film, or documentary. I never expected, however, that DNA would be the focus of a semi-documentary/semi-intellectual reality TV show, hosted by Stacey Dooley...

Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
CC BY 4.0
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false-coloured cryogenic scanning electron micrograph).
News
23 August 2019 • 2 minutes read

Mitochondria linked to stem cell transplant rejection

by Jen Willows

A new study has shown why stem cell transplants, even derived from the patient's own cells can be rejected...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
24 May 2019 • 2 minutes read

DNA study may have implications for mitochondrial donation

by Jenny Sharpe

Mitochondria are not as interchangeable as originally thought, with implications for the selection of donors for mitochondrial donation...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
10 May 2019 • 1 minute read

Native American man's DNA traced back 17,000 years

by Dr Sam Sherratt

A Native American man in Montana has the 'oldest' human DNA in the United States, according to news reports...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
CC0 1.0
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
News
12 April 2019 • 2 minutes read

First baby born in mitochondrial donation for infertility trial

by Catherine Heffner

A baby conceived via IVF using genetic information from three people has been born to a mother not affected by mitochondrial disease...

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4 July 2022 • 4 minutes read

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Join PET and Genomics England to celebrate the 200th birthday of Gregor Mendel

27 June 2022 • 4 minutes read

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Children's rights and donor conception: What next?

20 June 2022 • 4 minutes read

The problems with lifting donor anonymity earlier

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